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Steroidogenesis-related gene expression in the rat ovary exposed to melatonin s...
Lima, Gisele Negro; Maganhin, Carla Cristina; Simões, Ricardo Santos; Baracat, Maria Cândida Pinheiro; Sasso, Gisela Rodrigues da SilvaOBJECTIVE: To analyze steroidogenesis-related gene expression in the rat ovary exposed to melatonin supplementation. METHODS: Thirty-two virgin adult female rats were randomized to two groups as follows: the control group GI received vehicle and the experimental group GII received melatonin supplementation (10 µg/night per animal) for 60 consecutive days. After the treatment, animals were anesthetized and the c...
Assessing the benefits of rosiglitazone in women with polycystic ovary syndrome...
Batista, José Gomes; Soares-Jr, José Maria; Maganhin, Carla Cristina; Simões, Ricardo Santos; Tomaz, Geraldez; Baracat, Edmund Chada
Effects of pentoxifylline on TNF-alpha and lung histopathology in HCL-induced l...
Oliveira-Júnior, Itamar Souza de; Maganhin, Carla Cristina; Carbonel, Adriana Aparecida Ferraz; Monteiro, Cristina Maria RodriguesOBJECTIVE: To evaluate the effects of pentoxifylline on hydrochloric acid-induced lung lesions in rats subjected to mechanical ventilation. METHODS: Twenty male, adult Wistar-EPM-1 rats were anesthetized and randomly grouped (n=5 animals per group) as follows: control-MV (mechanical ventilation, MV group); bilateral instillation of HCl (HCl group); bilateral instillation of HCl followed by pentoxifylline (50 mg...