9 documents found, page 1 of 1

Recent advances and strategies for nanocarrier-mediated topical therapy and the...

Posterior eye disorders, such as age-related macular degeneration, diabetic retinopathy, and glaucoma, have a significant impact on human quality of life and are the primary cause of age-related retinal diseases among adults. There is a pressing need for innovative topical approaches to treat posterior eye disorders, as current methods often rely on invasive procedures with inherent risks. Limited success was a...

PEDIATRIC HYPERTENSION - THE ROLE OF THE GENERAL PRACTITIONER IN HIGHLIGHTING A...

Blood Pressure (BP) assessment within Primary Health Care (CSP) surveillance consultations results from the recognition of a growing importance of Hypertension (HTN) problematic at a young age. Hypertension is defined by systolic and / or diastolic BP above the 95th percentile (P). Secondary hypertension is more frequent in pre-adolescent children and the main etiology are renal causes. Due to treatable cause o...

Electrospun fibers for vaginal administration of tenofovir disoproxil fumarate ...

Women are particularly vulnerable to sexual HIV-1 transmission. Oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate and emtricitabine (TDF/FTC) is highly effective in avoiding new infections in men, but protection has only been shown to be moderate in women. Such differences have been associated, at least partially, to poor drug penetration of the lower female genital tract and the need for ...

Avobenzone-loaded and omega-3-enriched lipid formulations for production of UV ...

Given the growing harmful effects of ultraviolet (UV) radiation there is an urgent need to develop effective strategies to prevent skin damages. Therefore, hydrogel or cotton and wool fabrics were impregnated with avobenzone (AVO)-loaded and omega-3 (ω3)-enriched lipid formulations (liposomes – LIP, nanostructured lipid carriers – NLC and solid lipid nanoparticles – SLN) to obtain UV blocking sunscreen gel or f...

Lipid nanocarriers for anti-HIV therapeutics: a focus on physicochemical proper...

Since HIV was first identified, and in a relatively short period of time, AIDS has become one of the most devastating infectious diseases of the 21st century. Classical antiretroviral therapies were a major step forward in disease treatment options, significantly improving the survival rates of HIV-infected individuals. Even though these therapies have greatly improved HIV clinical outcomes, antiretrovirals (AR...

Integração não-formal de migrantes e refugiados em Portugal - Projeto Integrararte

O projeto ocorreu no âmbito de um mestrado, com duas famílias refugiadas. O estado português assegura-lhes o acesso ao subsistema escolar e ao SNS, sendo quase omissos projetos de médio-longo prazos no âmbito não formal e informal. Foi construído com (e não para) a população, onde semanalmente se realizaram várias atividades agrupadas em ateliers, sendo continuamente ajustável, Os ateliers focaram-se, mas não e...

TDF/FTC electrospun nanofibers for topical prevention of HIV transmission

Human immunodeficiency virus (HIV) is still a problem for global health so, there is a strong need to develop effective microbicides that can be used safely to protect from infection during sexual intercourse. This pre-exposure prophylaxis (PrEP) may be formulations containing oral or topical microbicides. Topical formulations have advantages as they are suitable for vaginal or rectal application and allow a hi...

A importância da Internet como ferramenta de comunicação no Banco Espírito Sant...

O âmbito principal deste relatório de estágio é perceber a importância que vários elementos de um website corporativo têm na comunicação de um banco de investimento. O estágio foi realizado de Setembro de 2013 até Maio de 2014, num dos maiores bancos de investimento no território nacional, o Banco Espírito Santo de Investimento, S.A. Neste período, as funções por mim desempenhadas focaram-se no acompanhamento, ...

Avaliação da vulnerabilidade à contaminação de águas subterrâneas pelo método D...