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Involvement of cerebral nervous system areas and cytokines on antihyperalgesic ...
Melo, M.S.; Brito, R.G.; Santos, P.L.; Nogueira, P.C.L.; Moraes, V.R.S.; Matos, M.C.P.; Ferro, J.N.S.; Barreto, E.O.; Lucca Júnior, Waldecy deKielmeyera rugosa is a medicinal plant known in Northeastern Brazil as ‘pau-santo’, and it is used in the treatment of several tropical diseases such as malaria, schistosomiasis, and leishmaniasis. We evaluated antihyperalgesic and anti-inflammatory activities of methanol stem extract of K. rugosa (MEKR) in mice. The mechanical hyperalgesia induced by carrageenan and tumor necrosis factor-alpha (TNF-α), prostag...
Date: 2014
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Origin: Oasisbr