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Retraction notice to " IP1867B suppresses the Insulin-like Growth Factor 1 Rece...
Mihajluk, K.; Simms, C.; Reay, M.; A Madureira, Patricia; Howarth, A.; Murray, P.; Nasser, S.; Duckworth, C.A.; Pritchard, D.M.; Pilkington, G.J.This article has been retracted at the request of the Editor-in-Chief due to concerns regarding the legitimacy of images and data presented in the paper. Though a corrigendum (Can. Lett. Vol. 469, 2020, pages 524–535) was previously published to address some of these concerns, this corrigendum has also been found to contain errors and therefore cannot stand. Specific concerns are listed below.
Corrigendum to IP1867B suppresses the insulin-like growth factor 1 receptor (IG...
Mihajluk, K.; Simms, C.; Reay, M.; A Madureira, Patricia; Howarth, A.; Murray, P.; Nasser, S.; Duckworth, C. A.; Pritchard, D. M.; Pilkington, G. J.
The role of hypoxia in glioblastoma invasion
Monteiro, Ana; Hill, Richard; Pilkington, Geoffrey; A Madureira, PatriciaGlioblastoma multiforme (GBM), a grade IV astrocytoma, is the most common and deadly type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 to 17 months. The current treatment for GBM involves tumor resection surgery based on MRI image analysis, followed by radiotherapy and treatment with temozolomide. However, the gradual development of tumor resistance to temozolomide is ...
Gemcitabine-mediated tumour regression and p53-dependent gene expression: impli...
Hill, Richard; Rabb, M.; A Madureira, Patricia; Clements, D.; Gujar, S. A.; Waisman, D. M.; Giacomantonio, C. A.; Lee, P. W. K.Gemcitabine is a chemotherapeutic that is widely used for the treatment of a variety of haematological malignancies and has become the standard chemotherapy for the treatment of advanced pancreatic cancer. Combinational gemcitabine regimes (e.g. with doxorubicin) are being tested in clinical trials to treat a variety of cancers, including colon cancer. The limited success of these trials has prompted us to purs...