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Natalizumab treatment for multiple sclerosis: updates and considerations for sa...

Nali,Luiz Henrique da Silva; Moraes,Lenira; Fink,Maria Cristina Domingues; Callegaro,Dagoberto; Romano,Camila Malta; Oliveira,Augusto Cesar Penalva de

Natalizumab is currently one of the best options for treatment of patients with Multiple Sclerosis who have failed traditional prior therapies. However, prolonged use, prior immunosuppressive therapy and anti-JCV antibody status have been associated with increased risk of developing progressive multifocal leukoencephalopathy (PML). The evaluation of these conditions has been used to estimate risks of PML in the...

Date: 2014   |   Origin: Oasisbr
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