4 documents found, page 1 of 1
Treatment of iron overload syndrome: a general review
Lima,Tadeu Gonçalves de; Benevides,Fernanda Luna Neri; Esmeraldo Filho,Flávio Lima; Farias,Igor Silva; Dourado,Diovana Ximenes CavalcanteSUMMARY INTRODUCTION Iron overload is a broad syndrome with a large spectrum of causative etiologies that lead to iron deposition. When iron exceeds defenses, it causes oxidative damage and tissular disfunction. Treatment may prevent organ dysfunction, leading to greater life expectancy. METHODS Literature from the last five years was reviewed through the use of the PubMed database in search of treatment strate...
Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-...
Cruz,Rossilene Conceição da Silva; Bührer-Sékula,Samira; Penna,Gerson Oliveira; Moraes,Maria Elisabete Amaral de; Gonçalves,Heitor de SáAbstract: BACKGROUND: The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen, assessed the adverse effects caused by the drugs. OBJECTIVE: Describe adverse effects due to MDT in U-MDT/CT-BR, comparing the uniform regimen (U-MDT) to the current WHO regimen (R-MDT). Patients and methods: After operational classi...
Identification of mechanisms involved in the relaxation of rabbit cavernous smo...
Cerqueira,João Batista Gadelha de; Gonzaga-Silva,Lúcio Flávio; Silva,Francisco Ordelei Nascimento da; Cerqueira,João Victor Medeiros dePURPOSE: The aim of this study was to evaluate the relaxation in vitro of cavernous smooth muscle induced by a new NO donor of the complex nitrosil-ruthenium, named trans-[Ru(NH3)4(caffeine)(NO)]C13 (Rut-Caf) and sodium nitroprusside (SNP). MATERIALS AND METHODS: The tissues, immersed in isolated bath systems, were pre-contracted with phenilephrine (PE) (1 µM) and then concentration-response curves (10-12 - 10-...
Modelo experimental de tumor na cavidade oral de ratos com carcinossarcoma de W...
Alves,Ana Paula Negreiros Nunes; Guedes,Rafael Cardoso; Costa-Lotufo,Letícia Veras; Moraes,Maria Elisabete Amaral de; Pessoa,Cláudia do ÓOBJETIVO: Estabelecer um modelo experimental de desenvolvimento tumoral na cavidade oral de ratos, permitindo, assim, o estudo da osteólise induzida pelo tumor nos ossos do complexo maxilomandibular como também nas estruturas dentais, através da caracterização histomorfológica da reabsorção óssea e dentária. MÉTODOS: Uma suspensão de células tumorais (0,1mL) do Carcinossarcoma de Walker 256, na concentração de ...