3 documents found, page 1 of 1
Optimization and validation of an HPLC-DAD method for the identification of 14 ...
Morais, Ana F.; Fertig, Robin; Dinis-Oliveira, Ricardo Jorge; Ribeiro, Carlos J. A.Background: Cannabis sp. plant has its origins in East Asia, where it was initially used for recreational and religious purposes. This plant encompasses hundreds of chemical compounds, including phytocannabinoids, terpenoids, and flavonoids. The cannabinoids of greatest medicinal interest are Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), which are present in the plant in their acid form [1]. Sativex® ...
Analysis of terpenes in cannabis by GC-MS: method development and its applicati...
Capita, Albertina M.; Morais, Ana F.; Dinis-Oliveira, Ricardo Jorge; Ribeiro, Carlos J. A.; Silva, Eduarda M. P.Background: In addition to cannabinoids, key bioactive compounds in cannabis, terpenes and terpenoids, also have therapeutic importance, potentially working synergistically through their entourage effect for the medicinal efficacy of this plant [1,2]. Besides their therapeutic advantages, they are also responsible for the characteristic aroma of numerous varieties of cannabis, ranging from citrus to woody...
GC-MS-Based Study of 14 Cannabinoids Separation in Cannabis sativa L. Extracts ...
Nunes, Bruna A. S.; Capita, Albertina M.; Morais, Ana F.; Dinis-Oliveira, Ricardo J.; Ribeiro, Carlos J. A.; Silva, Eduarda M. P.Background: Cannabinoids from Cannabis sativa L. are increasingly studied due to their potential as medicinal drugs, offering therapeutic benefits such as pain relief and anti-inflammatory effects, while also raising concerns as substances of abuse due to their psychoactive properties [1,2]. Gas chromatography-mass spectrometry (GC-MS) is a powerful tool for identifying and quantifying cannabinoids, offering hi...