23 documents found, page 1 of 3
Factorial structure, measurement invariance and reliability of the Emotion Regu...
Fernandes, Marília; Morais, Inês; Santos, Carolina; Guedes, Maryse; Ribeiro, Olívia; Fernandes, Carla; Pires, Eva; Santos, Ana FilipaEmotion regulation is important for socioemotional and mental health development, with lifelong implications. The Emotion Regulation Checklist (ERC; Shields & Cicchetti, 1997) is a widely used tool to assess emotional regulation and dysregulation in children. Despite wide use and translate into several languages, inconsistent findings have been found in its factorial structure across studies. This study address...
Can the kindergarten teacher's behavior shape children's participation, communi...
Morais, Inês; Azevedo, Ana Rita; Fernandes, Isabel; Fuertes, MarinaEarly child development is greatly influenced by individual experiences (physical, motor, and sensory) and social interactions. Learning about how the adult interacts and communicates influences the child's actions and participation. In this research, we intend to study the adult role as a social and pedagogical model for children aged between 2 and 3 years during a joint construction play activity and understa...
N-Myristoyltransferase Inhibition in Parasitic Pathogens
Campos, Fernanda de França Genuíno Ramos; Moura, Willian Charles da Silva; Romário-Silva, Diego; de Araújo, Rodrigo Santos Aquino; Morais, InêsNeglected tropical diseases (NTDs) constitute a group of infectious diseases that severely affect the health of impoverished populations, and the health, economies, and health systems of affected countries. Leishmaniasis and human African trypanosomiasis (HAT) are particularly notable, and malaria, despite not being neglected, is part of the “big three” (HIV, tuberculosis, and malaria) with high incidence, incr...
Clinical Characteristics and Functional Outcomes After Rehabilitation in Femora...
Moreira, Sofia Sousa; Assunção, Sandra; Ribeiro, André; Cabete Martins, Sara; Morais, Inês; Machado Santos, Joana; Rodrigues, TeresaIliopsoas haematoma is an uncommon but potentially severe complication, most frequently associated with anticoagulation therapy. When voluminous, it may compress the femoral nerve, leading to disabling motor and sensory deficits. We report three elderly patients, all anticoagulated, who developed femoral neuropathy secondary to iliopsoas haematomas. Clinical presentations ranged from acute abdominal and groin p...
Design, Synthesis, and Antimalarial Evaluation of New Spiroacridine Derivatives
Cavalcanti, Misael de Azevedo Teotônio; Albino, Sonaly Lima; Menezes, Karla Joane da Silva; de Araújo, Wallyson Junio SantosBackground/Objectives: Malaria is a tropical disease mainly caused by Plasmodium falciparum and represents a global public health problem, with over 200 million cases and 500 thousand deaths reported worldwide. Considering its treatment limitations, it is essential to develop new compounds against malaria. In this context, acridine derivatives are privileged structures. Methods: Thus, new spiroacridines contain...
Heparin Induced Thrombocytopenia In The Setting Of Urgent Cardiac Surgery: Can ...
Alves, Bárbara; Veiga, Joana; Morais, Inês; Lima, Fátima; Paulo, NelsonUnfractionated heparin is the main anticoagulant employed in the context of cardiovascular surgery. When a patient with heparin induced thrombocytopenia (HIT) is proposed for cardiac surgery, the anticoagulation management is challenging. Bivalirudin is an alternative to heparin in the perioperative setting. We present a rare case of a patient with HIT and cardiogenic shock that required bivalirudin use in the ...
EBV infection and expression of HER2 and CD34 in gastric cancer, how are they r...
Mendes, Fernando; Pinheiro, Alexandra; Rocha, Clara; Melo, Fernando; Morais, Inês; Colaço, Inês; Andrade, Sara; Caetano, Rui; Carreira, PatríciaIntroduction: Gastric cancer (GC), as a multifactorial disease, exhibits a complex pathogenesis, having intra- and inter-tumor heterogeneity, challenging the efficacy of current treatments[1,2]. GC as a major global health problem, better diagnostic and therapeutic strategies are needed, leading to further biomarkers research associated to innovative targeted therapies[3,4]. Objectives: Our aim was to study hum...
The Walsh Family Resilience Questionnaire: Validity evidence from Portugal
Morais, Inês; Teplitzky Carneiro, Francis Anne; Sinval, J.; Costa, Pedro Alexandre; Leal, I.Background: Family resilience refers to a family’s capacityto face and manage adversities, emerging as a stronger andmore resourceful unit. A family system approach enlargesthe lens to the broad relational network, identifying poten-tial resources for resilience within the immediate andextended family. This approach emphasizes a family’sinnate ability to adapt in the face of adversities.Objective: This study ai...
Factorial structure, measurement invariance and reliability of the Emotion Regu...
Fernandes, Marília; Morais, Inês; Santos, Carolina; Guedes, Maryse; Ribeiro, Olívia; Fernandes, Carla; Pires, Eva; Santos, Ana FilipaAbstract: Emotion regulation is important for socioemotional and mental health development, with lifelong implications. The Emotion Regulation Checklist (ERC; Shields & Cicchetti, 1997) is a widely used tool to assess emotional regulation and dysregulation in children. Despite wide use and translate into several languages, inconsistent findings have been found in its factorial structure across studies. This stu...
High efficacy of chloroquine-derived bile salts in Pluronic F127 micelles again...
Silva, Ana Teresa; Prudêncio, Miguel; Oliveira, Isabel S.; Nogueira, Fátima; Morais, Inês; Santana, Sofia; Ferraz, Ricardo; Workneh, Eyob A.Colloidal nanocarriers can play a key role in the efficacious delivery of drugs, including antimalarials. Here, we investigated the ability of polymeric micelles of the block copolymer F127 to act as nanovehicles for two organic salts derived from chloroquine and human bile acids, namely, chloroquinium cholate (iCQP1) and chloroquinium glycocholate (iCQP1g). We have previously reported the strong in vitro antip...