23 documents found, page 1 of 3
Effectiveness of global postural reeducation in postural changes and postural s...
Pacheco, Maria Paula; Morais, Sara; Carvalho, Paulo José; Cavalheiro, Luís; Sousa, Filipa; Carvalho, PauloPostural changes are considered a public health issue and have gathered significant interest in both research and clinical practice. To evaluate the effectiveness of Global Postural Reeducation (GPR) in improving postural changes and postural stability in healthy young adults. Additionally, this study aims to identify the main postural changes in the sample population. A longitudinal study was conducted with a ...
Cooperação Educacional Brasil-Moçambique: Considerações sobre discursos de mode...
Morais, SaraDiscuto neste artigo aspectos da cooperação internacional brasileira no âmbito de acordos educacionais com Moçambique. Argumento como a implantação de grandes investimentos agrícolas e a difusão de telenovelas desempenham um papel central na execução desses acordos, ao promoverem imagens atrativas de um Brasil de riqueza e de oportunidades. À luz do exame de narrativas de duas gerações de moçambicanos que estud...
Intrahospital Protocol for the Management of COVID-19 Disease in Adults
Barreiro, Ivo; Matos, Marta; de Oliveira, Miguel; Guerra, Diogo; Fonseca, Tomás; Abreu, Miguel; Morais, Sara; Barbosa, GustavoThe COVID-19 pandemic is currently responsible for over 526 million infections and over 6.3 million deaths. As a new disease, the number of papers on the subject is extensive, motivating considerable heterogeneity in its approach. Despite some medicines having sound evidence of benefit, new interventions and strategies continue to be proposed, and some still lack scientific evidence, which hinders a uniform and...
Imunoterapia no cancro de mama triplo-negativo: o papel dos inibidores de check...
Branco, Susana; Graça, Maria Inês; Morais, SaraO cancro de mama triplo-negativo (TNBC) é um subtipo agressivo de cancro de mama, associado a um mau prognóstico em estadios iniciais e avançados. A quimioterapia continua a ser o tratamento padrão preconizado para estes doentes, apesar de seu benefício limitado. Devido às características agressivas da doença e à falta de terapias dirigidas, várias tentativas foram feitas para investigar novos alvos moleculares...
Immunotherapy in triple-negative breast cancer: the role of immune checkpoint i...
Branco, Susana; Graça, Maria Inês; Morais, SaraABSTRACT - Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer, associated with a poor prognosis in both early and advanced stages. Chemotherapy remains the standard treatment for these patients, despite its limited benefit. Due to the disease’s aggressive features and lack of targeted therapies, several attempts have been made to disclose novel molecular targets. TNBC is now known to...
Wide spectrum of F9 variants in hemophilia B families from the Portuguese popul...
Moreira, Isabel; Diniz, Maria João; Tavares, Alice; Morais, Sara; Freitas, B.; Araújo, F.; Gago, T.; Antunes, EM; Catarino, C.; Campos, M.; Almeida, T.Introduction: Hemophilia B is an X-linked bleeding disorder caused by molecular defects in the Factor IX gene (F9), leading to either deficiency or functional abnormality of Factor IX. Actual data indicate a high heterogeneity of variants in F9. Over 1000 different variants have been reported, including pathogenic single nucleotide variants (SNPs), indels and complex variants. Materials and Methods: 86 index pa...
Aggressive Neuroblastoma in a Pediatric Patient with Severe Hemophilia A
Costa, Lídia; Couto, Maria Eduarda; Moutinho, Juliana; Ferreira, Ana Maia; Costa, Emilia; Roncon, Susana; Santos, Luisa Lopes; Cruz, EugéniaDespite the extensive information regarding hemophilia's hemorrhagic complications, the literature on cancer in hemophilia is scarce, especially in pediatric patients. Many uncertainties remain concerning diagnosis and workup. We report a rare case of two severe diseases (neuroblastoma and hemophilia A (HA)) concomitantly present in the same pediatric patient. We highlight that the diagnosis of severe HA did no...
Guidelines on COVID-19 Vaccine Induced Thrombosis, Bleeding, and Thrombocytopenia
Morais, Sara; Cruz, EugéniaAfter widespread vaccination with COVID-19 vaccines, there have been worldwide reports on thrombosis, bleeding, and thrombocytopenia. Recently, a rare syndrome with a high mortality rate consisting of an unusual combination of thrombocytopenia and thrombosis, in particular cerebral venous sinus thrombosis, which clinically resembles heparin-induced thrombocytopenia, was reported following vaccination. Different...
Alternatives to the traditional backpack: a scope review about proposal models
Silva, Sandra; Gonçalves, Nadine; Morais, Sara; Salgado, Ana; Pinho, Liliana; Pinho, FranciscoThe backpack, when used correctly, is the healthiest and most frequent way of transporting material, by schoolchildren. However, represents a considerable external perturbation that can lead to postural changes.
Guidelines on: COVID-19 Vaccine Induced Thrombosis, Bleeding, and Thrombocytopenia
Morais, Sara; Cruz, EugéniaAfter widespread vaccination with COVID-19 vaccines, there have been worldwide reports on thrombosis, bleeding, and thrombocytopenia. Recently, a rare syndrome with a high mortality rate consisting of an unusual combination of thrombocytopenia and thrombosis, in particular cerebral venous sinus thrombosis, which clinically resembles heparin-induced thrombocytopenia, was reported following vaccination. Different...