7 documents found, page 1 of 1
GLP-1 Increases Circulating Leptin Levels in Truncal Vagotomized Rats
Morais, T; Pereira, SS; Andrade, S; Neves, D; Guimaraes, M; Nora, M; Carreira, MC; Casanueva, FF; Monteiro, MPGLP-1 is a gastro-intestinal hormone acting within the gut/brain axis for energy balance regulation. We aimed to evaluate the role of the vagus nerve in whole-body energy homeostasis and in mediating GLP-1 effects. For this, rats submitted to truncal vagotomy and sham-operated controls underwent a comprehensive evaluation, including eating behavior, body weight, percentage of white (WAT) and brown adipose tissu...
T1 Signal Intensity in the Dentate Nucleus After the Administration of the Macr...
Ramalho, J; Semelka; Cruz, J; Morais, T; Ramalho, MIntroduction and aims: Contradictory results have been reported about hyperintensity of the globus pallidus and/or dentate nucleus on unenhanced T1-weighted magnetic resonance (MR) images after exposure to various gadolinium-based contrast agents. This change in signal intensity varies with different gadolinium-based contrast agents. We aimed to determine whether signal intensity in the dentate nucleus is incre...
Endovascular Treatment of Pediatric Ischemic Stroke: a Single Center Experience...
Fragata, I; Morais, T; Silva, R; Paiva Nunes, A; Loureiro, P; Martins, JD; Pamplona, J; Carvalho, R; Baptista, M; Reis, JIntroduction: Mechanical thrombectomy is standard treatment for large vessel occlusion (LVO) in adults. There are no randomized controlled trials for the pediatric population. We report our single-center experience with thrombectomy of LVO in a series of pediatric patients, and perform a review of the literature. Methods: Retrospective review of consecutive pediatric thrombectomy cases between 2011 and 2018. De...
Use of flash glucose monitoring for post-bariatric hypoglycaemia diagnosis and ...
Lobato, CB; Pereira, SS; Guimarães, M; Morais, T; Oliveira, P; de Carvalho, JPM; Nora, M; Monteiro, MPOur aim was to assess the potential of flash glucose monitoring (FGM) for diagnostic workup of suspected post-bariatric hypoglycaemia (PBH). Patients (N = 13) with suspected PBH underwent a food and symptoms diary (FSD) record along with FGM over 14 days. Targeted data analysis confirmed the occurrence of low glucose events in parallel to meal-triggered symptoms. Glycaemic variability, as assessed by Mean Absol...
Accessing Non-Atherosclerotic Vasculopathies Using Ultrasound-Doppler Imaging
Ferreira Pinheiro, C; Morais, T; Perry da Câmara, C; Rios, C; Diogo, MC; Ferreira, MPThe non-atherosclerotic vasculopathies are an uncommon group of disorders, with diverse etiopathogenesis, involving younger patients when compared with atherosclerotic disease. Clinical presentation varies from acute vascular events - ischemic or hemorrhagic- to uncharacteristic neurologic syndromes. Although the cerebral angiography is the gold standard diagnostic method due to its high sensibility, its specif...
Acute effect of an amino acid mixture in the rat glycemic profile
Pena, MJ; Guerreiro, SG; rocha, jc; Morais, T; Pereira, SS; Monteiro, MP; Borges, NunoAmino acid mixtures (AAM) are protein substitutes used for phenylketonuria treatment, but their metabolic effects have not been well characterized. The objective of this study was to compare the acute glycemic response to free amino acids (free AA) from AAM with the response to intact protein (iProtein). Male Wistar rats (n = 14) were administered by gavage a bolus of free AA (n = 7) or iProtein as albumin (n =...
Prostate cancer cells are able to interact with surrounding adipocytes inducing...
Moreira, A; Pereira, S S; Andrade, S; Rodrigues, A; Santos, M; Morais, T; Gouveia, Alexandra; Monteiro, M P