5 documents found, page 1 of 1
Efeito pró-cinético da Mangiferina, isolada de Mangifera indica L., em camundongos
Morais, Talita CavalcanteMangiferin is a glucosylxanthone encountered in several traditionally used medicinal plants that has been shown to exhibit multiple pharmacological effects that include antioxidant, anti-inflammatory and gastroprotective. Mangiferin used in this study was extracted and isolated from the stem bark of Mangifera indica L. (mango), and its prokinetic effect was investigated using experimental models of gastrointest...
Topical anti-inflammatory potential of Physalin E from Physalis angulata on exp...
Pinto, Natália Bitú; Morais, Talita Cavalcante; Carvalho, Karine Maria Martins Bezerra; Silva, Cecília Rocha; Andrade, Geanne Matos deThe anti-inflammatory effect of physalin E, a seco-steroid isolated from Physalis angulata L. was evaluated on acute and chronic models of dermatitis induced by 12-O-tetradecanoyl-phorbol-13- acetate (TPA) and oxazolone, respectively, in mouse ear. The changes in ear edema/thickness, production of pro-inflammatory cytokines (TNF- a and IFN- g ), myeloperoxidase (MPO) activity, and histological and immunohistoch...
Peripheral antinociceptive action of mangiferin in mouse models of experimental...
Lopes, Synara C.; Silva, Ana Virgínia Lima da; Arruda, Bruno Rodrigues; Morais, Talita Cavalcante; Rios, Jeison Barros Rioshis study aimed to assess the possible systemic antinociceptive activity of mangiferin and to clarify the un- derlying mechanism, using the acute models of chemical (acetic acid, formalin, and capsaicin) and thermal (hot-plate and tail- fl ick) nociception in mice. Mangiferin at oral doses of 10 to 100 mg/kg evidenced signif- icant antinociception against chemogenic pain in the test models of acetic acid-induce...
Mangiferin, a natural xanthone, accelerates gastrointestinal transit in mice in...
Morais, Talita Cavalcante; Lopes, Synara Cavalcante; Carvalho, Karine Maria Martins Bezerra; Arruda, Bruno Rodrigues; Souza, Francisco Thiago Correia deAIM: To investigate the effects of mangiferin on gas - trointestinal transit (GIT) in normal and constipated mice, together with the possible mechanism. METHODS: Intragastrically-administered charcoal mea was used to measure GIT in overnight starved Swiss mice. In the first experiments, mangiferin (3 mg/kg, 10 mg/kg, 30 mg/kg, and 100 mg/kg, po ) or tegaserod (1 mg/kg, ip ) were administered 30 min before the c...
Efeito analgésico, antiinflamatório e gastroprotetor dos ácidos anacárdicos, is...
Morais, Talita CavalcanteThe anacardic acids (AA), isolated from cashew nut-shell liquid of popular medicinal plant Anacardium occidentale (cajueiro, Anacardiaceae) and were shown to possess antioxidant, lipoxygenase inhibitory, anti-Helicobacter pylori and antitumor properties were evaluated and pharmacologically characterized for the first time using the animal models of nociception (acetic acid writhing. formalin, capsaicin, and hot...