9 documents found, page 1 of 1
Assessing medication use patterns by clinical outcomes severity among inpatient...
Ferreira-da-Silva, Renato; Maranhão, Priscila; Dias, Cláudia Camila; Alves, João Miguel; Pires, Ligia; Morato, Manuela; Polónia, Jorge JunqueiraPurpose: This study assessed medication patterns for inpatients at a central hospital in Portugal and explored their relationships with clinical outcomes in COVID-19 cases. Methods: A retrospective study analyzed inpatient medication data, coded using the Anatomical Therapeutic Chemical classification system, from electronic patient records. It investigated the association between medications and clinical sever...
Heterogeneity in protocols and outcomes to study the effect of renin‐angiotensi...
Ferreira‐Duarte, Mariana; Tonin, Fernanda; Duarte‐Araújo, Margarida; Fernandez‐Llimos, Fernando; Morato, ManuelaBackground: The renin-angiotensin system (RAS) has been associated with inflammatory bowel disease (IBD), supporting the translational relevance of RAS blockers. Comparability of study design/outcomes is fundamental for data analysis/discussion. Objectives: We aimed at evaluating the heterogeneity among protocols and outcomes to study the effect of angiotensin-converting enzyme inhibitors or angiotensin recepto...
The Role of Pharmacovigilance in the COVID-19 Pandemic
Ferreira-da-Silva, Renato; Ribeiro-Vaz, Inês; Morato, Manuela; Silva, Ana Marta; Junqueira Polónia, JorgeN/a.; N/a.
Pullulan microneedle patches for the efficient transdermal administration of in...
Fonseca, Daniela F. S.; Costa, Paulo C.; Almeida, Isabel F.; Dias-Pereira, Patrícia; Correia-Sá, Inês; Bastos, Verónica; Oliveira, HelenaThe present study reports the fabrication of dissolvable microneedle (MN) patches using pullulan (PL), a water-soluble polysaccharide with excellent film-forming ability, for the transdermal administration of insulin, envisioning the non-invasive treatment of diabetes. PL MNs patches were successfully prepared by micromoulding and revealed good thermal stability (Tdmax = 294 °C) and mechanical properties (>0.15...
Decrease in the expression of NMDA receptors in the nucleus tractus solitarii i...
Pinho, Dora; Albino-Teixeira, Antonio; Tavares, Isaura; Morato, Manuela; Martins, Isabel; Marques-Lopes, José; Wilson, Steven P
Hypoalgesia and increased blood pressure induced by decreased expression of NMD...
Lopes, José Marques; Martins, Isabel; Pinho, Dora; Morato, Manuela; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura[abstract]
Pain and blood pressure modulation upon knockdown of NMDA receptor in the nucle...
Lopes, José Marques; Martins, Isabel; Pinho, Dora; Morato, Manuela; Wilson, Steven P.; Teixeira, António Albino; Tavares, Isaura[abstract]
Effect of 2-chloroadenosine on sodium and potassium excretion in diabetic Wista...
Patinha, Daniela; Morato, Manuela; Afonso, Joana; Pinho, Dora; Correia, Catarina; Albino-Teixeira, António
Hipertensão e hipoalgesia: papel do bolbo raquidiano ventrolateral caudal e do ...
Pinho, Dora; Morato, Manuela; Sousa, Teresa; Marques-Lopes, José; Tavares, Isaura; Albino-Teixeira, António