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Studies on the biocompatibility of bacterial cellulose.

Alexandre, Nuno; Andrade, Fábia; Amorim, Irina; Gartner, Fátima; Maurício, Ana Colette; Luís, Ana Lúcia; Gama, Miguel

Bacterial cellulose was functionalized with a chimeric protein containing a cellulose-binding module and the adhesion peptide Arg-Gly-Asp. Small-diameter bacterial cellulose membranes were produced and subcutaneously implanted in sheep for 1–32 weeks. The implants triggered a biological response similar to other high surface-to-volume implants. There were no significant differences in the inflammation degree be...


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