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Hydrogel and membrane scaffold formulations of Frutalin (breadfruit lectin) wit...

Sousa, Felipe Domingos de; Vasconselos, Pedrinha Diógenes; Silva, Ayrles Fernanda Brandão da; Mota, Erika Freitas; Tomé, Adriana da Rocha

Plant lectins are carbohydrate-binding proteins, which can interact with cell surfaces to initiate anti-inflammatory pathways, as well as immunomodulatory functions. Here, we have extracted, purified and part-characterized the bioactivity of Jacalin, Frutalin, DAL and PNA, before evaluating their potential for wound healing in cultured human skin fibroblasts. Only Frutalin stimulated fibroblast migration in vit...

Date: 2021   |   Origin: Oasisbr

Caracterização estrutural de três lectinas apresentando especificidades por açú...

Moreira, Ana Cristina de Oliveira Monteiro

Three lectins from Artocarpus incisa L. seeds, showing different sugar-binding properties, were efficiently isolated and purified by affinity chromatography. The D-galaetose-binding lectin was isolated on an Adenanthera pavonina L. cross-linked galactomannan while the D-mannose-binding leetin was isolated on agarose-mannose and the chitin binding lectins was isolated on chitin columns. These lectins were named ...

Date: 2019   |   Origin: Oasisbr

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