The melioidosis is an emerging infectious disease, especially in northeastern Brazil, with serious international implications, as well as a public health problem. Caused by the bacillus Burkholderia pseudomallei, this infection appears from tables asymptomatic to severe and often fatal frames. The high mortality rate of the disease (20-50%) make it a priority for global health agencies. In Brazil, cases of meli...
This study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim- sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly high...
Historically, bacteria have been seen as isolated organisms; however, it is now clear that the vast majority of bacteria exist in complex communities known as biofilms. Bacteria in biofilms are adhered to various surfaces, both abiotic and biotic (teeth, bones, mucosa), often forming a highly dynamic ecosystem, which is structured and organized. An example of infection, which can involve the formation of biofil...
Corpos estranhos (CE) são motivos freqüentes de consultas em Otorrinolaringologia. Os sítios mais comumente acometidos são cavidade nasal, orelhas e faringe. Nestes locais os corpos estranhos apresentam sintomas característicos e a remoção destes não representa grande dificuldade para o especialista. A forma de inoculação pode ser voluntária ou acidental1,2. A ocorrência de corpos estranhos em seios paranasais ...