13 documents found, page 1 of 2

Prospective Study of Loss of Health-Related Quality Adjusted Life Years in Chil...

Introduction and aims: Although usually benign, varicella can lead to serious complications and sometimes long-term sequelae. Vaccines are safe and effective but not yet included in immunisation programmes in many countries. We aimed to quantify the impact on health-related quality of life (HRQoL) in terms of quality-adjusted life years (QALY) in children with varicella and their families, key to assessing cost...

Personality characteristics of victims of intimate partner violence: A systemat...

The best CRISPR/Cas9 versus RNA interference approaches for Arabinogalactan pro...

Arabinogalactan Proteins (AGPs) are hydroxyproline-rich proteins containing a high proportion of carbohydrates, widely spread in the plant kingdom. AGPs have been suggested to play important roles in plant development processes, especially in sexual plant reproduction. Nevertheless, the functions of a large number of these molecules, remains to be discovered. In this review, we discuss two revolutionary genetic...

Occupational Health and Its Influence on Job (Dis)Satisfaction

Immature Personality Disorder: Contribution to the Definition of this Personality

Insights into secrets along the pollen tube pathway in need to be discovered

The process of plant fertilization provides an outstanding example of refined control of gene expression. During this elegant process, subtle communication occurs between neighboring cells, based on chemical signals, that induces cellular mechanisms of patterning and growth. Having faced an immediate issue of self-incompatibility responses, the pathway to fertilization starts once the stigmatic cells recognize ...

PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal...

Drug delivery to the central nervous system is restricted by the blood-brain barrier (BBB). However, with the onset of stroke, the BBB becomes leaky, providing a window of opportunity to passively target the brain. Here, cationic poly(amido amine) (PAMAM) dendrimers of different generations were functionalized with poly(ethylene glycol) (PEG) to reduce cytotoxicity and prolong blood circulation half-life, aimin...

A Closed Loop Brain-machine Interface for Epilepsy Control Using Dorsal Column ...

Although electrical neurostimulation has been proposed as an alternative treatment for drug-resistant cases of epilepsy, current procedures such as deep brain stimulation, vagus, and trigeminal nerve stimulation are effective only in a fraction of the patients. Here we demonstrate a closed loop brain-machine interface that delivers electrical stimulation to the dorsal column (DCS) of the spinal cord to suppress...

Depression and Psychotherapy: The Importance of a Psychotherapeutic Approach Fo...

Many patients who show up with depressive and anxious symptomology have, or have had, interpersonal conflicts that triggered or contributed to the aggravation of the symptomology herein explained. Clinical experience has taught us that many people have difficulty in maintaining Faultless Logical Reasoning (FLR) and, even if FLR is present, they have difficulty in maintaining Faultless Logical Functioning (FLF)....

AMPK in Pathogens

During host-pathogen interactions, a complex web of events is crucial for the outcome of infection. Pathogen recognition triggers powerful cellular signaling events that is translated into the induction and maintenance of innate and adaptive host immunity against infection. In opposition, pathogens employ active mechanisms to manipulate host cell regulatory pathways toward their proliferation and survival. Amon...