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The antioxidant peptide salamandrin-i: First bioactive peptide identified from ...

Plácido, A; Bueno, J; Barbosa, EA; Moreira, DC; Dias, JDN; Cabral, WF; Albuquerque, P; Bessa, LJ; Freitas, J; Kuckelhaus, SAS; Lima, FCDA

Amphibian skin is a multifunctional organ that plays key roles in defense, breathing, and water balance. In this study, skin secretion samples of the fire salamander (Salamandra salamandra) were separated using RP-HPLC and de novo sequenced using MALDI-TOF MS/MS. Next, we used an in silico platform to screen antioxidant molecules in the framework of density functional theory. One of the identified peptides, sal...


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