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Obesity impairs resistance to Leishmania major infection in C57BL/6 mice.

Martins, Vinicius Dantas; Campos, Franciele Carolina Silva; Moreira, Felipe Caixeta; Carneiro, Matheus Batista Heitor; Goes, Grazielle Ribeiro

An association between increased susceptibility to infectious diseases and obesity has been described as a result of impaired immunity in obese individuals. It is not clear whether a similar linkage can be drawn between obesity and parasitic diseases. To evaluate the effect of obesity in the immune response to cutaneous Leishmania major infection, we studied the ability of C57BL/6 mice fed a hypercaloric diet (...

Date: 2020   |   Origin: Oasisbr
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