4 documents found, page 1 of 1
Efeitos cardiovasculares do citral, monoterpeno majoritário do óleo essencial d...
Moreira, Flávia VianaCoordenação de Aperfeiçoamento de Pessoal de Nível Superior; The monoterpene citral is the major constituent of the essential oil of Cymbopogon citratus, medicinal plant popularly known as capim-limão or capim-santo , widely used to treat hypertension. This study evaluated the cardiovascular effects induced by the citral in normotensive rats by using in vivo and in vitro approaches. In non-anaesthetized rats, c...
Chemical composition and cardiovascular effects induced by the essential oil of...
Moreira, Flávia Viana; Bastos, Joana Ferreira Alves; Blank, Arie Fitzgerald; Alves, Péricles Barreto; Santos, Márcio Roberto Viana dosC. citratus é utilizada na medicina popular para tratar hipertensão. Este trabalho investigou a composição química e os efeitos cardiovasculares do óleo essencial do C. citratus (OECC). Foram identificados oito constituintes no OECC, sendo geranial o majoritário (43,08%). Em ratos, o OECC (1, 5, 10 e 20 mg/kg, i.v.) induziu hipotensão e bradicardia que foram atenuadas pela atropina e tiopental sódico, mas não p...
Carvacrol, (−)-borneol and citral reduce convulsant activity in rodents
Quintans-Júnior, Lucindo José; Guimarães, Adriana Gibara; Araújo, Bruno Eduardo Silva de; Cavalcanti, Sócrates Cabral de HolandaCarvacrol, a monoterpenic phenol present in essential oils of the Labiatae family, has been used through the ages as a source of flavor in food and for medicinal purposes. Borneol is a monoterpene found in several species of Artemisia and Dipterocarpaceae, used for anxiety, pain and anesthesia in traditional Chinese. Citral, a mixture of two geometrical isomers (neral and geranial), is one of the most important...
Citral reduces nociceptive and inflammatory response in rodents
Quintans-Júnior, Lucindo José; Guimarães, Adriana Gibara; Santana, Marília Trindade de; Araújo, Bruno Eduardo Silva de; Moreira, Flávia VianaCitral (CIT), which contains the chiral enantiomers, neral (cis) and geranial (trans), is the majority monoterpene from Lippia alba and Cymbopogon citratus. The present study aimed to evaluate CIT for antinociceptive and anti-inflammatory activities in rodents. Antinociceptive and anti-inflammatory effects were studied by measuring nociception through acetic acid and formalin tests, while inflammation was verif...