[Excerto] No dia a dia somos submersos por notícias e acontecimentos que testam a nossa confiança sobre a possibilidade de construirmos uma sociedade de confiabilidade estável, respeitadora da individualidade e da diversidade. Somos bombardeados com propaganda e amostras de produtos comerciais relacionados com a procura de felicidade típica do animal sadio, por contraponto à tristeza do animal vadio: maçãs feli...
During the first COVID-19 related confinement in Portugal, there was a decrease in the levels of psychological symptoms measured by the Depression, Anxiety and Stress Scale 21 (March to April 2020). Upon experiencing a new period of restraints in 2021, the psychological impact of this sample was assessed again (<i>N</i> = 322, two more time points). It was expected that the psychological symptoms evidenced in F...
Takotsubo syndrome (TTS) is an acute, reversible cardiomyopathy. The central autonomic nervous system (ANS) is believed to play a role in this disease. The aim of the present study was to investigate the patterns of brain functional connectivity in a sample of patients who had experienced a previous episode of TTS. Brain functional connectivity, both at rest and in response to the stressful stimulus of topical ...
Background: Laboratory practice commonly implies rodent anesthesia. Such is instrumental not only for animal welfare, but also for standardized assessment of new anesthetics. New method: We developed and validated a grading system for a temporal follow-up of anesthesia. The Minho Objective Rodent Phenotypical Anesthesia (MORPhA) scale was tested in mice (C57BL/6 J) and rats (WistarHan) anesthetized with ketamin...
In this work, we assessed the reliability of a low-cost psychophysiological system - the James One device - to monitor the electrodermal activity during an emotion induction paradigm. We observed that during emotional expression in response to negative stimuli, participants displayed increased amplitudes of the skin conductance responses, in comparison to the natural observation of neutral pictures and to emoti...
Chronic pain is frequently accompanied by the manifestation of emotional disturbances and cognitive deficits. While a causality relation between pain and emotional/cognitive disturbances is generally assumed, several observations suggest a temporal dissociation and independent mechanisms. We therefore studied Sprague-Dawley rats that presented a natural resistance to pain manifestation in a neuropathy model (sp...
As human beings, we are constantly making decisions. Decision-making involves the ability of selecting among different alternatives to produce a given outcome. Due to the crucial relevance of decision-making in our everyday living, its study has been progressively established in the scientific literature. In addition, the study of the neurobiological mechanisms underlying these processes has been applied to som...
Impulsivity is a naturally occurring behavior that, when accentuated, can be found in a variety of neuropsychiatric disorders. The expression of trait impulsivity has been shown to change with a variety of factors, such as age and sex, but the existing literature does not reflect widespread consensus regarding the influence of modulating effects. We designed the present study to investigate, in a cohort of sign...
Introduction: Haemophilia is related to several clinical and psychosocial challenges that have been associated with increased emotional distress. These may impact on disease adjustment and health outcomes, reinforcing the attention given to psychosocial health of people with haemophilia (PWH), in the scope of optimal comprehensive care. Aim: To identify potentially modifiable factors associated with the presenc...
In this work, we examined the longitudinal measurement invariance of a battery composed of distinct cognitive parameters. A sample of 86 individuals (53.5% females; mean age = 65.73), representative of the Portuguese older population, with respect to sex, age and level of education was assessed twice over an average of two years. By means of a confirmatory factor analysis approach, we tested whether a two-facto...