3 documents found, page 1 of 1
Hydroxycinnamic acids and curcumin production in engineered Escherichia coli us...
Rodrigues, Joana L.; Couto, Márcia; Araújo, R.; Kristala L. J. Prather; Kluskens, Leon; Rodrigues, L. R.Supplementary data associated with this article can be found, inthe online version, at http://dx.doi.org/10.1016/j.bej.2017.05.015.; Hydroxycinnamic acids and curcumin are compounds with great therapeutic potential, including anticancer properties. In this study, p-coumaric acid, caffeic acid and curcumin were produced in Escherichia coli. Their production was induced by heat using the dnaK and ibpA heat shock ...
Enhancing curcuminoid production using E. coli engineered strains
Couto, Márcia; Rodrigues, Joana Lúcia Lima Correia; Rodrigues, L. R.Curcuminoids are natural secondary metabolites from the herb Curcuma longa. Their beneficial properties, mainly as anti-cancer agents, have been exhaustively reported but the therapeutic effect of curcumin is limited by its fast systemic elimination along with poor bioavailability. Besides, curcumin extraction from plants is very expensive and it is hard to synthetize chemically. For these reasons, the use of m...
Hemoglobinopatias no Distrito Federal, Brasil
Tavares-Neto, J.; Naoum, Paulo C. [UNESP]; Adorno, José; Azevêdo, Paula; Brito, Fátima; Caldas, Márcia; Couto, Márcia; Costa, KarinaSubmitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:05:46Z No. of bitstreams: 1 S0037-86821986000100004.pdf: 304693 bytes, checksum: 8370b894523affc68ab3207e5330bd14 (MD5); Made available in DSpace on 2013-08-22T19:05:46Z (GMT). No. of bitstreams: 1 S0037-86821986000100004.pdf: 304693 bytes, checksum: 8370b894523affc68ab3207e5330bd14 (MD5) Previous issue date: 1986-03-01; Made availabl...