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Hydrogel and membrane scaffold formulations of Frutalin (breadfruit lectin) wit...

Sousa, Felipe Domingos de; Vasconselos, Pedrinha Diógenes; Silva, Ayrles Fernanda Brandão da; Mota, Erika Freitas; Tomé, Adriana da Rocha

Plant lectins are carbohydrate-binding proteins, which can interact with cell surfaces to initiate anti-inflammatory pathways, as well as immunomodulatory functions. Here, we have extracted, purified and part-characterized the bioactivity of Jacalin, Frutalin, DAL and PNA, before evaluating their potential for wound healing in cultured human skin fibroblasts. Only Frutalin stimulated fibroblast migration in vit...

Date: 2021   |   Origin: Oasisbr

Protein fractions, amino acid composition and antinutritional constituents of h...

Vasconcelos, Ilka Maria; Maia, Fernanda Maria Machado; Farias, Davi Felipe; Campello, Claudio Cabral; Carvalho, Ana Fontenele Urano

High-yielding cowpea (Vigna unguiculata) cultivars were analysed for major changes in seed protein types, amino acid profiles and antinutritional factors content. As usual, the globulins constitute the major seed proteins (493.2–573.3 g kg 1 total seed protein), followed by albumins (201.0–248.0 g kg 1 ), basic glutelins (119.1–154.3 g kg 1 ), acid glutelins (82.4–92.3 g kg 1 ) and prolamins (13.2–20.2 g kg 1 )...

Date: 2021   |   Origin: Oasisbr


Ethanol-induced gastric injury : microscopic analysis of the protective effect ...

Abdon, Ana Paula Vasconcellos; Vasconcelos, Renata Prado; Castro, Carolina Araújo; Guedes, Marjorie Moreira; Tomé, Adriana da Rocha

Obtained from breadfruit seeds (Artocarpus incisa), frutalin (FTL) has a range of important pharmacological properties. FTL activates and modulates lymphocytes and neutrophils and possesses gastroprotective effects. The purpose of this study was to evaluate the ability of FTL to protect the gastric mucosa of mice submitted to ethanolinduced gastric injury. The gastroprotective effect of frutalina was evaluated ...

Date: 2014   |   Origin: Oasisbr


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