24 documents found, page 1 of 3

A tale of two (un)Just Transitions: the end of the coal-fired power plants in P...

This paper explores the social, economic, and environmental impacts of the closures of Portugal's two coal-fired power plants—Sines and Pego—in 2021, within the context of the Just Transition framework. Through a case study approach, it explores how the shutdown affected workers, communities, and regional economies, based on stakeholder discourses from government officials, unions, companies, and municipalities...

Impérios, comidas e viagens de pessoas e plantas: entrevista com Cristiana Bastos

O Estado social que a Constituição abriu e as sementes de Estado ambiental que ...

Brain-targeted drug delivery - nanovesicles directed to specific brain cells by...

Neurodegenerative diseases are characterized by extensive loss of function or death of brain cells, hampering the life quality of patients. Brain-targeted drug delivery is challenging, with a low success rate this far. Therefore, the application of targeting ligands in drug vehicles, such as lipid-based and polymeric nanoparticles, holds the promise to overcome the blood-brain barrier (BBB) and direct therapies...

Corrigendum: Methylmercury impact on adult neurogenesis: is the worst yet to co...

[This corrects the article DOI: 10.3389/fnagi.2020.591601.].

Establishment and characterization of human pluripotent stem cells-derived brai...

The establishment of robust human brain organoids to model cerebellar diseases is essential to study new therapeutic strategies for cerebellum-associated disorders. Machado-Joseph disease (MJD) is a cerebellar hereditary neurodegenerative disease, without therapeutic options able to prevent the disease progression. In the present work, control and MJD induced-pluripotent stem cells were used to establish human ...

Extracellular Vesicles Physiological Role and the Particular Case of Disease-Sp...

Recent research demonstrated pathological spreading of the disease-causing proteins from one focal point across other brain regions for some neurodegenerative diseases, such as Parkinson's and Alzheimer's disease. Spreading mediated by extracellular vesicles is one of the proposed disease-spreading mechanisms. Extracellular vesicles are cell membrane-derived vesicles, used by cells for cell-to-cell communicatio...

Methylmercury Impact on Adult Neurogenesis: Is the Worst Yet to Come From Recen...

Worldwide environmental tragedies of anthropogenic origin causing massive release of metals and other pollutants have been increasing considerably. These pollution outbreaks affect the ecosystems and impact human health. Among those tragedies, recent large-scale environmental disasters in Brazil strongly affected riverside populations, leading to high-risk exposure to methylmercury (MeHg). MeHg is highly neurot...

Wall screen: An ultra-high definition video-card for the internet of things

8 k ultra-high definition (UHD) is paving the way for the next-generation video systems. In the audiovisual industry, besides delivering a more immersive experience, it is a mean to smooth spatial artifacts during video sampling. In the medical industry, it may provide surgeons with increased reality in surgeries such as endoscopy. Nevertheless, researchers are struggling to meet the high throughput required by...

PORTOMESENTERIC VENOUS GAS AND INTESTINAL PNEUMATOSIS – RADIOLOGICAL SIGNS OF M...

Computed tomography showing portal and mesenteric venous gas and intestinal pneumatosis, rare radiological signs that, together, favor the diagnosis of mesenteric ischemia (70% of cases). When present, mortality is around 40-90%. Surgical exploration is mandatory with assessment of the extent of intestinal ischemia and appropriate treatment.