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Association of statin use on survival outcomes of patients with early-stage HER...

Purpose There is evidence that statins might improve the outcome of patients with breast cancer. The role of statins in patients with early HER2-positive breast cancer is unknown. Therefore, we explored the association between statin use and survival outcomes in early HER2-positive breast cancer patients in the phase III APHINITY trial (adjuvant pertuzumab/ trastuzumab). Methods All patients (intent-to-treat po...

Correction to: Surgery of the primary tumor in patients with de novo metastatic...

In the original publication of the article, the following article note has been missed to include. “Mariana Brandão and Diogo Martins-Branco have contributed equally to this work.” The original article has been corrected.

Acute total occlusion of the unprotected left main coronary artery: Patient cha...

Introduction and objectives: Acute total occlusion of the unprotected left main coronary artery (LMCA) is a dramatic event. There are limited data regarding this population. We aimed to describe the clinical presentation and outcomes of patients and to determine predictors of in-hospital mortality. Methods: This retrospective study included patients presenting with acute (<12 h) myocardial infarction due to tot...

O papel do enfermeiro da unidade de cuidados intensivos no combate à resistênci...

Myocardial deformation analysis using cardiac magnetic resonance in apical hype...

Apical hypertrophic cardiomyopathy (AHCM) has a broad phenotypic spectrum and still poses many diagnostic and prognostic challenges. Our team performed a retrospective study to examine the prognostic value of myocardial deformation obtained with cardiac magnetic resonance tissue tracking (CMR-TT) analysis in predicting adverse events in AHCM patients. We included patients with AHCM referred to CMR in our depart...

Hyponatremia in Cancer Patients Hospitalized in a Palliative Care Department: A...

Introduction: Hyponatremia is frequent in cancer patients, as many studies carried out in these patients have shown. However, there are only a few studies carried out at the end of life and in palliative care. The aim of this study was to determine the prevalence of hyponatremia in cancer patients in the palliative care department of an oncology center and its association with survival.Material and Methods: The...

Window of Opportunity for Immunodulatory Therapy in COVID-19

The COVID-19 pandemic is a serious public health problem worldwide, for which there is no effective therapies. About 20%-33% of patients are admitted to intensive care units and in these the mortality rate is higher than 25%. Death caused directly by the COVID-19 results, in most cases, from an inappropriate hyperinflammatory response to the infection, with the release of cytokines. Due to the parallelism with ...

Avaliação do Exame Final do Internato Médico em Portugal

Introdução: Existe uma elevada heterogeneidade na estrutura da avaliação da formação médica pós-graduada a nível mundial. No entanto, contrastando com outros países, não existem estudos científicos em Portugal que tenham avaliado o modelo da avaliação final da especialidade. O presente estudo pretendeu avaliar a adequação do exame do final da especialidade aos seus propósitos; aí incluída a sua validade enquant...

Evaluation of The Medical Board Exam in Portugal

Introduction: There is a high heterogeneity in the structure of postgraduate medical training evaluation worldwide. However, in contrast to other countries, there have been no scientific studies of the final medical board examination, in Portugal. The present study aimed to evaluate the adequacy of the medical board examination including its validity as measured by its association with medical school grade aver...

Marjolin’s Ulcer with Axillary Lymph Node Metastasis

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