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Characterization and outcomes of pulmonary alveolar proteinosis in Brazil: a ca...
Athayde,Rodolfo Augusto Bacelar de; Arimura,Fábio Eiji; Kairalla,Ronaldo Adib; Carvalho,Carlos Roberto Ribeiro; Baldi,Bruno GuedesABSTRACT Objective: Pulmonary alveolar proteinosis (PAP) is a rare disease, characterized by the alveolar accumulation of surfactant, which is composed of proteins and lipids. PAP is caused by a deficit of macrophage activity, for which the main treatment is whole-lung lavage (WLL). We report the experience at a referral center for PAP in Brazil. Methods: This was a retrospective study involving patients with P...
Obesity hypoventilation syndrome: a current review
Athayde,Rodolfo Augusto Bacelar de; Oliveira Filho,José Ricardo Bandeira de; Lorenzi Filho,Geraldo; Genta,Pedro RodriguesABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, ...