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Quantifying the legacy of the Chinese Neolithic on the maternal genetic heritag...

Brandão, Andreia; Eng, Ken Khong; Rito, Teresa S; Cavadas, Bruno; Bulbeck, David; Gandini, Francesca; Pala, Maria; Mormina, Maru; Hudson, Bob

There has been a long-standing debate concerning the extent to which the spread of Neolithic ceramics and Malay-Polynesian languages in Island Southeast Asia (ISEA) were coupled to an agriculturally driven demic dispersal out of Taiwan 4000 years ago (4 ka). We previously addressed this question using founder analysis of mitochondrial DNA (mtDNA) control-region sequences to identify major lineage clusters most ...


HLA polymorphism in six malay subethnic groups in Malaysia

Edinur, Hisham Atan; Zafarina, Zainuddin; Spínola, Hélder; Nurhaslindawaty, Abd Rashid; Panneerchelvam, Sundararajulu; Norazmi, Mohd-Nor

In this study, human leukocyte antigen (HLA) class I and II were examined through sequence-specific primer typing in 176 unrelated individuals from six Malay subethnic groups of Peninsular Malaysia: Kelantan (n = 25), Minangkabau (34), Jawa (30), Bugis (31), Banjar (33), and Rawa (23). The most common HLA alleles in all groups were A*24 (26–41%), Cw*07 (24–32%), B*15 (22–30%), DRB1*12 (15–36%), and DQB1*03 (25–...


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