3 documents found, page 1 of 1
Crotacetin, a Novel Snake Venom C-Type Lectin Homolog of Convulxin, Exhibits an...
Rádis-Baptista, Gandhi; Moreno, Frederico Bruno Mendes Batista; Nogueira, Lucas de Lima; Martins, Alice M. C.; Toyama, Daniela de OliveiraSnake venom (sv) C-type lectins encompass a group of hemorrhagic toxins that are capable of interfering with blood stasis. A very well-studied svC-type lectin is the heterodimeric toxin, convulxin (CVX), from the venom of South American rattlesnake Crotalus durissus terrificus. CVX is able to activate platelets and induce their aggregation by acting via p62/GPVI collagen receptor. By using polymerase chain reac...
Lectin genes and their mature proteins: Still an exciting matter, as revealed b...
Fernandes, Andréia Varmes; Ramos, Márcio Viana; Costa, José Hélio; Vasconcelos, Ilka Maria Aria; MOREIRA, Renato A.Two new lectins were purified through affinity chromatography after crude extract preparation under high ionic strength. The hemagglutinating activity of these lectins from the seeds of the legumes Dioclea bicolor (DBL) and Deguelia scandens (DSL) was inhibited by galactose and glucose, respectively, and the molecular masses were estimated at 24 and 22kDa (via SDS-PAGE), respectively. The alignment of internal ...
Effects of piperonal nitro derivatives on candida species : antifungal activity...
Andrade Neto, João Batista de; Silva, Cecília Rocha da; Campos, Rosana de Sousa; Nascimento, Francisca Bruna Stefany Aires do; Freitas, Daniel DominguesRecently, there has been a significant increase in invasive fungal infections, the treatment of which is limited to a quite small number of antifungal drugs. Natural products represent an important source of antifungal agents, mainly because of their natural coexistence with fungi present in each biome. Derivatives or semi-synthetic products can be used to optimize the pharmacological profile of natural product...