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Prognosticating the Outcome of Intensive Care in Older Patients - a Narrative R...

Beil, M; Moreno, R; Fronczek, J; Kogan, Y; Moreno, R; Flaatten, H; Guidet, B; de Lange, D; Leaver, S; Nachshon, A; van Heerden, P; Joskowicz, L

Prognosis determines major decisions regarding treatment for critically ill patients. Statistical models have been developed to predict the probability of survival and other outcomes of intensive care. Although they were trained on the characteristics of large patient cohorts, they often do not represent very old patients (age ≥ 80 years) appropriately. Moreover, the heterogeneity within this particular group i...



OPTImized Coronary Interventions EXplaIn the BEst CliNical OutcomEs (OPTI-XIENC...

Moreno, R; Bravo Baptista, S; Valencia, J; Gomez-Menchero, A; Bouisset, F; Ruiz-Arroyo, JR; Bento, A; Besutti, M; Jimenez-Valero, S; Rivero-Santana, B

Introduction: Clinical events may occur after percutaneous coronary intervention (PCI), particularly in complex lesions and complex patients. The optimization of PCI result, using pressure guidewire and intracoronary imaging techniques, may reduce the risk of these events. The hypothesis of the present study is that the clinical outcome of patients with indication of PCI and coronary stent implantation that are...


The Sequential Organ Failure Assessment (SOFA) Score: Has the Time Come for an ...

Moreno, R; Rhodes, A; Piquilloud, L; Hernandez, G; Takala, J; Gershengorn, H; Tavares, M; Coopersmith, C; Myatra, S; Singer, M; Rezende, E; Prescott, H

The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring organ dysfunction in critically ill patients. Changes in clinical practice over the last few decades, with new interventions and a greater focus on non-invasive monitoring systems, mean it is time to update the SOFA score. As a first step in this process, we propose so...



Association of Chronic Heart Failure with Mortality in Old Intensive Care Patie...

Romano Bruno, R; Wernly, B; Wolff, G; Fjølner, J; Artigas, A; Bollen Pinto, B; Schefold, J; Kindgen‐Milles, D; Baldia, P; Kelm, M; Beil, M; Sviri, S

Aims: Chronic heart failure (CHF) is a major risk factor for mortality in coronavirus disease 2019 (COVID-19). This prospective international multicentre study investigates the role of pre-existing CHF on clinical outcomes of critically ill old (≥70 years) intensive care patients with COVID-19. Methods and results: Patients with pre-existing CHF were subclassified as having ischaemic or non-ischaemic cardiac di...


Increased 30-Day Mortality in Very Old ICU Patients with COVID-19 Compared to P...

Guidet, B; Jung, C; Flaatten, H; Fjølner, J; Artigas, A; Bollen Pinto, B; Schefold, J; Beil, M; Sigal, S; Vernon van Heerden, P; Szczeklik, W

Purpose: The number of patients ≥ 80 years admitted into critical care is increasing. Coronavirus disease 2019 (COVID-19) added another challenge for clinical decisions for both admission and limitation of life-sustaining treatments (LLST). We aimed to compare the characteristics and mortality of very old critically ill patients with or without COVID-19 with a focus on LLST. Methods: Patients 80 years or older ...


Transcutaneous Electrical Diaphragmatic Stimulation Reduces the Duration of Inv...

Duarte, G; Bethiol, A; Ratti, L; Franco, G; Moreno, R; Tonella, R; Falcão, AL

Study design: Retrospective case series. Objectives: To compare individuals with cervical spinal cord injury (SCI) submitted to transcutaneous electrical diaphragmatic stimulation (TEDS) or a standard weaning protocol (SWP) according to the following variables: invasive mechanical ventilation (IMV) time, ventilator weaning time, intensive care unit (ICU) length of stay, and overall hospital length of stay. Sett...



Equilibrating SSC Guidelines with Individualized Care

Vincent, JL; Singer, M; Einav, S; Moreno, R; Wendon, J; Teboul, JL; Bakker, J; Hernandez, G; Annane, D; de Man, A; Monnet, X; Ranieri, V; Hamzaoui, O


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