3 documents found, page 1 of 1
Systems Biology in ELIXIR: modelling in the spotlight
Martins dos Santos, V; Anton, M; Szomolay, B; Ostaszewski, M; Arts, I; Benfeitas, R; Dominguez Del Angel, V; Ferk, P; Fey, D; Goble, C; Golebiewski, MIn this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community believes that the infrastructure aspects of systems biology - databases, (modelling) tools and standards development, as well as training and access to cloud infrastruc...
DNA damage in circulating leukocytes measured with the comet assay may predict ...
Bonassi, S; Ceppi, M; Møller, P; Azqueta, A; Milić, M; Neri, M; Brunborg, G; Godschalk, R; Koppen, G; Langie, SAS; Teixeira, JP; Bruzzone, MThe comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, mortality by cause, and cancer incidence associated to DNA damage, a cohort of 2,403 healthy individuals (25,978 person-years) screened in 16 laboratories using the comet assay between 1996 and 2016 was fol...
The hCOMET project: International database comparison of results with the comet...
Milić, M; Ceppi, M; Bruzzone, M; Azqueta, A; Brunborg, G; Godschalk, R; Koppen, G; Langie, S; Møller, P; Teixeira, JP; Alija, A; Anderson, D; Andrade, VThe alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification of those factors that can explain the large inter-individual and inter-laboratory variation. International collaborative initiatives such as the hCOMET project - a COST Action launched in 2016 - represent...