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Appraising Animal Models of Prostate Cancer for Translational Research: Future ...

Nascimento Gonçalves, Elisabete; Seixas, Fernanda; Da Costa, Rui M. Gil; Pires, Maria Joao; Neuparth, Maria Joao; Moreira-Goncalves, Daniel

The growing incidence of prostate cancer has prompted a great investment in basic biology and translational studies to develop new therapies. Multiple animal models have been established to study etiological factors, cancer-preventive strategies and the molecular determinants of aggressiveness and metastases. The rat model of prostate cancer induced by chemical carcinogen N-methyl-N-nitrosourea (MNU) and testos...


Effect of the dog positioning on X-ray table on hip dysplasia parameter evaluation

Martins, João; Colaco, Bruno; Alves-Pimenta, Sofia; Orden, JMG; Ferreira, AJ; M, Ginja

ABSTRACT - Objective The aim of this study was to evaluate the effect of pelvic tilting along the long axis and femoral rotation on Norberg angle (NA), subluxation index (SI) and subluxation category (SC) in the standard ventrodorsal hip extended (VDHE) radiographical view on live animals. Study Type This was a retrospective clinical study. Materials and Methods Pairs of VDHE views, one adequately positioned an...


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