31 documents found, page 1 of 4
Acute Kidney Injury and Electrolyte Imbalances Caused by Dapagliflozin Short-Te...
Lopes, António Cabral; Lourenço, Olga; Morgado, Sandra; Gaspar, Andreia; Freire, Idalina; Eusébio, Inês; Ribeiro, João; Silva, Mafalda; Mendes, MartaDapagliflozin, a sodium–glucose cotransporter 2 inhibitor (SGLT2i), has shown demonstrated benefits for renal and cardiovascular outcomes in large clinical trials. However, short-term concerns regarding its impact on renal function and electrolyte balance exist. This study aimed to evaluate the short-term effects of dapagliflozin on renal function and electrolyte balance in patients newly prescribed the medicat...
Position of the Specialized Section of Oncology of the Portuguese Society of He...
Morgado, Manuel; Fernandes, Armandina; Santos, Bárbara; Mimoso, Cecília; Soares, Cristina; Santos, Jorge Bigotte; da Silva, Sofia Carvalho.; .
Management of the Adverse Effects of Immune Checkpoint Inhibitors
Morgado, Manuel; Plácido, Ana; Morgado, Sandra; Roque, FátimaBy increasing the activity of the immune system, immune checkpoint inhibitors (ICPI) can have adverse inflammatory effects, which are referred to as immune-related adverse effects (irAEs). In this review, we present the recommendations for the appropriate identification and treatment of irAEs associated with ICPI to increase the safety and effectiveness of therapy with these immuno-oncological drugs. Several gu...
Arbutus unedo L.: From traditional medicine to potential uses in modern pharmac...
Morgado, Sandra; Morgado, Manuel; Plácido, Ana; Roque, Fátima; Duarte, Ana PaulaEthnopharmacological relevance: Arbutus unedo L., the strawberry tree (Ericaceae family) is of increasing interest because of its common traditional, industrial, chemical and pharmaceutical uses. The plant is a typical evergreen plant of the Mediterranean basin, as well as of other regions with hot summers and mild rainy winters. This review covers the studies relevant to Arbutus unedo L. utilization in the cur...
Drug-related Problems in Home-dwelling Older Adults: A Systematic Review
Plácido, Ana; Herdeiro, Maria; Morgado, Manuel; Figueiras, Adolfo; Roque, FátimaPurpose: The complex combination of medicines associated with age-related physiological alterations leads older adults to experience drug-related problems (DRPs). The goal of this study was to review the frequency and type of DRPs and DRP risk factors in home-dwelling older adults. Methods: A MEDLINE PubMed and EMBASE scientific databases search was performed. Articles published from January 2000 through Decemb...
Daily Medication Management and Adherence in the Polymedicated Elderly: A Cross...
Gomes, Daniel; Plácido, Ana; Mó, Rita; Simões, João; Amaral, Odete; Fernandes, Isabel; Lima, Fátima; Morgado, Manuel; Figueiras, Adolfo; Herdeiro, MariaThe presence of age-related comorbidities prone elderly patients to the phenomenon of polypharmacy and consequently to a higher risk of nonadherence. Thus, this paper aims to characterize the medication consumption profile and explore the relationship of beliefs and daily medication management on medication adherence by home-dwelling polymedicated elderly people. A questionnaire on adherence, managing, and beli...
Clinical pharmacists interventions in the management of type 2 diabetes mellitu...
Pousinho, Sarah; Morgado, Manuel; Plácido, Ana; Roque, Fátima; Falcão, Amílcar; Alves, GilbertoBackground: Type 2 diabetes mellitus is a chronic disease that is reaching epidemic proportions worldwide. It is imperative to adopt an integrated strategy, which involves a close collaboration between the patient and a multidisciplinary team of which pharmacists should be integral elements. Objective: This work aims to identify and summarize the main effects of interventions carried out by clinical pharmacists...
Trends and Geographic Variabilities in Benzodiazepines Prescription in Primary ...
Tavares, Ana; Plácido, Ana; Rodrigues, Daniela; Morgado, Manuel; Figueiras, Adolfo; Herdeiro, Maria; Roque, FátimaBackground: According to the World Health Organization (WHO), benzodiazepines (BZD) are considered essential medicines for the treatment of several mental disorders in older adults over 65 years old. However, the long-term use of BZD could present a harmful impact on this population, leading to cognitive deficits, drug dependence, falls, and fractures. This study aims to analyze trends of BZD prescription to Po...
Acceptance of Pharmaceutical Services by Home-Dwelling Older Patients: A Case S...
Paiva, Ana; Plácido, Ana; Curto, Isabel; Morgado, Manuel; Herdeiro, Maria; Roque, FátimaBackground: Aging-related comorbidities predispose older adults to polypharmacy and consequently an increased risk of adverse drug reactions and poor compliance. Pharmacists' interventions can have a beneficial impact on the improvement of clinical outcomes. Thus, this work aimed to assess the acceptance of Portuguese home-dwelling older adults regarding a pharmaceutical service paid by patients for medication ...
Ética ou Moral, ou Ética e Moral? | Ethics or Morals, or Ethics and Morals?
Morgado, ManuelEthics and morals are concepts simultaneously immersed today in two phenomena that contradict each other. On the one hand, the scientific literature assumes a total separation and distinction between them. On the other hand, they remain, currently but indiscriminately, used as synonyms. Now, what we defend in this exercise of reflection is that both this contradiction and the separation itself constitute the mo...