Background: Critical infrastructures (e.g., national security, energy systems, transport systems/supply chain, health, and telecommunications) (fig. 1) have been the target of constant cyber-attacks that debilitate the population's sense of security and have had profound economic, social, and public safety impacts [1,2]. Also, cyber-physical systems in smart cities face complex challenges that require robust cy...
Decadence and the protection of civilization are recurring themes in Raymond Aron’s thought. In particular, at the end of his career Aron reflected on the condition of the Western world and on the meaning of the word “decadence”. In this regard, Aron found Machiavelli’s work to be immensely helpful, to the point of equating decadence with the lack of what Machiavelli named virtù, or “historical vitality”. This ...
There is a pressing need for novel diagnostic and progression biomarkers of neurodegeneration. However, the inability to determine disease duration and stage in patients with Alzheimer’s disease (AD) hinders their discovery. Because animal models of disease allow us to circumvent some of these limitations, they have proven to be of paramount importance in clinical research. Due to the clear optics of the eye, t...
We present the initial stages of development of a Finite Element Method-based time-dependent elastic numerical model which seeks to support the employment of our Optical Coherence Elastography system for assessing murine retinal elasticity. The current model is able to reconstruct displacement maps in both homogeneous and heterogeneous domains with errors up to a few hundredths relatively to a known exact displ...
Robust methods to compute tissue displacements in optical coherence elastography (OCE) data are paramount, as they play a significant role in the accuracy of tissue elastic properties estimation. In this study, the accuracy of different phase estimators was evaluated on simulated OCE data, where the displacements can be accurately set, and on real data. Displacement (∆d) estimates were computed from (i) the ori...
Purpose: To investigate the effects of exercise training on cancer-related fatigue (CRF) in colorectal cancer survivors. Methods: Randomized controlled trials published between 1 January 2010 and 19 October 2020, selected through online search conducted in PubMed, Scopus, Web of Science, SPORTDiscus and PEDro databases, were included. Eligible trials compared the effect of exercise training interventions, versu...
Understanding the physical basis of corneal transparency has been a subject of interest amongst physicists, basic scientists and ophthalmologists. Impairment of corneal clarity is a significant cause of visual morbidity worldwide. Thus, it is essential to understand the mechanisms behind corneal transparency and how the alterations due to corneal pathologies affect vision. We use Maxwell’s equations to model li...
O presente manual foi desenvolvido por estudantes da Licenciatura em Fisioterapia (Unidade Curricular de Educação e Comunicação em Saúde) e investigadores do Centro de Inovação em Tecnologias e Cuidados de Saúde (ciTechCare) da Escola Superior de Saúde do Instituto Politécnico de Leiria, baseando-se num documento semelhante criado pela Associação Australiana de Ciências do Desporto. A informação apresentada bas...
Single-pixel imaging is an imaging technique that has recently attracted a lot of attention from several areas. This paper presents a study on the influence of the Hadamard basis ordering on the image reconstruction quality, using simulation and experimental methods. During this work, five different orderings, Natural, Walsh, Cake-cutting, High Frequency and Random orders, along with two different reconstructio...