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The dual nature of the BOLD signal: Responses in visual area hMT+ reflect both ...

Sousa, Teresa; Duarte, João V.; Costa, Gabriel Nascimento Ferreira da; Kemper, Valentin G.; Martins, Ricardo Filipe Alves; Goebel, Rainer

Neuroimaging studies have suggested that hMT+ encodes global motion interpretation, but this contradicts the notion that BOLD activity mainly reflects neuronal input. While measuring fMRI responses at 7 Tesla, we used an ambiguous moving stimulus, yielding the perception of two incoherently moving surfaces-component motion-or only one coherently moving surface-pattern motion, to induce perceptual fluctuations a...


Tracking perceptual decision mechanisms through changes in interhemispheric fun...

Sousa, Teresa; Duarte, João V.; Costa, Gabriel Nascimento Ferreira da; Kemper, Valentin G.; Martins, Ricardo Filipe Alves; Goebel, Rainer

The role of long-range integration mechanisms underlying visual perceptual binding and their link to interhemispheric functional connectivity, as measured by fMRI, remains elusive. Only inferences on anatomical organization from resting state data paradigms not requiring coherent binding have been achieved. Here, we used a paradigm that allowed us to study such relation between perceptual interpretation and fun...


Histological validation of high-resolution DTI in human post mortem tissue

Seehaus, Arne; Roebroeck, Alard; Bastiani, Matteo; Fonseca, Lúcia; Bratzke, Hansjürgen; Lori, Nicolás; Vilanova, Anna; Goebel, Rainer; Galuske, Ralf

Diffusion tensor imaging (DTI) is amongst the simplest mathematical models available for diffusion magnetic resonance imaging, yet still by far the most used one. Despite the success of DTI as an imaging tool for white matter fibers, its anatomical underpinnings on a microstructural basis remain unclear. In this study, we used 65 myelin-stained sections of human premotor cortex to validate modeled fiber orienta...


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