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Secondary metabolites of cyanobacteria from Cape Verde Archipelago act as NO do...

Morone, Janaína; Hentschke, Guilherme Scotta; Oliveira, Isabel Benta; Vasconcelos, Vítor; Martins, Rosário; Lopes, Graciliana; Martins, Rosário

Nitric oxide (NO) is a versatile mediator implicated in a variety of physiological processes, with the ultimate goal of maintaining organism homeostasis. In the present work, aqueous extracts from ten cyanobacteria strains isolated from the Cape Verde archipelago were explored as potential NO donors. None of the strains are toxin producers, as demonstrated by PCR and LC-MS analysis. The extracts were mainly com...


Carotenoids from cyanobacteria modulate iNOS and inhibit the production of infl...

Morone, Janaína; Vasconcelos, Vitor; Hentschke, Guilherme; Rosário Martins, Maria; Pinto, Eugénia; Lopes, Graciliana

Cyanobacteria are green multiproduct refineries of increasing interest for different industrial prospects. In this work, eleven cyanobacteria strains isolated from the Cape Verde archipelago were explored for their biotechnological applications in the field of inflammation. A biorefinery approach was employed to produce carotenoidtargeted extracts, further profiled by HPLC-PDA and explored for their ability to ...


Pigments profile and antioxidant potential of extremophile cyanobacteria isolat...

Silva, Raquel; Gonçalves, Talita; Morone, Janaína; Moreira, Gabriela Alves; Morais, João; Hentschke, Guilherme Scotta

Cyanobacteria are ancient and prolific microorganisms for which the current knowledge remains limited. The present work constitutes the first report on the presence of the cyanobacteria Tolypothrix sp. LEGE 221228, Nostoc sp. LEGE 221229, Scytonema sp. LEGE 221230 and Drouetiella sp. LEGE 221231 in the volcanic crater lake in Chichonal (Chiapas-Mexico), and in the characterization of their pigments profile and ...


Cyanobacteria for skin care and cosmeceutical formulations

Melo, Luísa; Morone, Janaína; Silva, Margarida; Ferraz, Ricardo; Martins, Rosário

Skin acts as a barrier from external stimulus such as pollutants and ultraviolet radiation. Disturbs in the skin are involved in skin aging, which mostly results on a thinner epidermis, dryness, wrinkles, and loss of elasticity. Synthetic ingredients in cosmetics are known to be more toxic and to cause negative impact on the environment. In a society increasingly worried with human and environment health, natur...


Cyanobacteria in cosmetics: a natural alternative for anti-aging ingredients

Morone, Janaína; Lopes, Graciliana; Oliveira, Beatriz; Vasconcelos, Vítor; Martins, Rosario

Being exposed to endogenous and exogenous stressors, and being the body’s external defense line, skin protection is of pivotal importance, in order to maintain morphological and physiologic integrity and health. Fostering by individual psychological comfort, esthetic performance, and young appearance, along with motivation for natural products with less side effects and sustainable production, consumer’s demand...


Cosmetic application of cyanobacteria extracts with a sustainable vision to ski...

Morone, Janaína; Lopes, Graciliana; Morais, João; Neves, Jorge; Vasconcelos, Vítor; Martins, Rosário

Nature-based and sustainably sourced cosmetics have been dominating the area of skincare products worldwide. Due to their antioxidant and antiaging properties, compounds from cyanobacteria, such as carotenoids and phycobiliproteins, may replace synthetic ingredients in cosmetic formulations and may be used in products such as sunscreens, skincare creams, and makeup. In this study, we evaluated the potential of ...


Cyanobacteria secondary metabolites as biotechnological ingredients in natural ...

Favas, Rita; Morone, Janaína; Martins, Rosário; Vasconcelos, Vitor; Lopes, Graciliana

The loss of density and elasticity, the appearance of wrinkles and hyperpigmentation are among the first noticeable signs of skin aging. Beyond UV radiation and oxidative stress, matrix metalloproteinases (MMPs) assume a preponderant role in the process, since their deregulation results in the degradation of most extracellular matrix components. In this survey, four cyanobacteria strains were explored for their...


Exploitation of filamentous and picoplanktonic cyanobacteria for cosmetic appli...

Morone, Janaína; Lopes, Graciliana; Preto, Marco; Vasconcelos, Vítor; Martins, Rosário

The use of natural products in skin care formulations gained interest as a concern formodern societies. The undesirable side effects of synthetic compounds, as well as the associatedenvironmental hazards, have driven investigation on photosynthetic organisms as sustainable sourcesof effective and environmentally friendly ingredients. The use of natural extracts in cosmetics hasbeen highlighted and, along with p...


Phytochemical profile, antioxidant activity and cytotoxicity against keratinocy...

Morone, Janaína; Lopes, Graciliana; Preto, Marco; Vasconcelos, Vítor; Martins, Rosário

Combining the increase demand for natural products in skin care formulations, and the bioactive arsenal of cyanobacteria, we aimed with this study to evaluate the potential of a 70% ethanolic extract of picocyanobacteria strains of the genera Cyanobium and Synechocystis for skin care applications.


Revealing the potential of cyanobacteria in cosmetics and cosmeceuticals — A ne...

Morone, Janaína; Alfeus, Anna; Vasconcelos, Vitor; Martins, Rosário

The growing concern over appearance, health and aging has driven the exploration for cosmetics based on natural sources. Alongside with plants, algae and eukaryotic microalgae, cyanobacteria have been explored for the isolation of compounds with potential application in the cosmetic and cosmeceutical field. The long evolutionary history of cyanobacteria and exposure to environmental stress conditions seems to b...


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