11 documents found, page 1 of 2

Evaluation of radiotherapy doses in pediatric patients with Hodgkin Lymphoma: M...

Background: Hodgkin lymphoma (HL) is one of the most common cancers in children, and radiotherapy (RT) is a crucial part of treatment [1,2]. However, the risk of late effects, such as cardiotoxicity and secondary malignant neoplasms, is a concern due to radiation exposure to critical organs [2-8]. Advanced dose calculation methods, such as Monte Carlo Methods (MCMs), can improve dosimetry accuracy and help mini...

Self-medication

Self-medication allows individuals to treat minor health issues without a medical prescription, facilitated by the availability of over-the-counter (OTC) medicines (May, L., Schaefer, M., & Tamburro, C., 2023). This practice requires healthcare professionals, particularly pharmacists, to play a key role in ensuring the safe and rational use of medicines (Pacha et al., 2023). Objectives: This study aimed to unde...

Self-medication

Self-medication allows individuals to treat minor health issues without a medical prescription, facilitated by the availability of over-thecounter (OTC) medicines [1,2]. This practice requires healthcare professionals, particularly pharmacists, to play a key role in ensuring the safe and rational use of medicines. Objectives: This study aimed to understand the motivations behind self-medication in Portugal and ...

Redefining ovarian cancer treatment with a first-in-class inhibitor of homologo...

Background: High-grade serous ovarian cancer (HGSOC) is characterized by poor prognosis and low overall survival. While PARP inhibitors (PARPis) are standard maintenance therapy for BRCA-mutated HGSOC (10% of cases), acquired resis-tance develops in over 60% of patients. We identied BBIT20, a rst-in-class inhibitor of the BRCA1-BARD1 interaction that disrupts homologous recombination (HR) DNA repair. Methods: B...

Enhancing the Production of Hydrolytic Enzymes in Elicited Tamarillo (Solanum b...

Plant cell suspension cultures are widely used as a tool for analyzing cellular and molecular processes, metabolite synthesis, and differentiation, bypassing the structural complexity of plants. Within the range of approaches used to increase the production of metabolites by plant cells, one of the most recurrent is applying elicitors capable of stimulating metabolic pathways related to defense mechanisms. Prev...

Screening of Candida albicans urinary tract infections by electronic nose

Fungus caused urinary tract infections (UTIs) are often misdiagnosed. Since culturing procedures are time-consuming, practitioners prophylactically prescribe antibiotics, which are ineffective. Hence, there is a need for reliable methods to detect infectious concentrations of fungi in urine. Since Candida spp is the main responsible for mycological UTI, this study focuses on the detection of candiduria by analy...

Detection and identification of fungal species by electronic nose technology: A...

A rapid and effective identification of fungal species is essential for numerous applications, and electronic nose systems are being proposed as suitable alternatives to currently available fungi identification techniques. Hence, the present review aims to unveil all published information concerning fungi identification by electronic nose systems. A systematic review of the literature was conducted according to...

Assessing the efficacy of A weight loss program for Adults with obesity: Prelim...

Abordagem e Registo da Anafilaxia em Portugal

A anafilaxia apresenta uma incidência crescente, particularmente em idade pediátrica. Constituindo uma emergência médica, o sucesso terapêutico depende de uma intervenção precoce e adequada. A adrenalina por via intramuscular constitui o fármaco de eleição para o seu tratamento, devendo a dose ser ajustada ao peso e à idade. Resolvida a reação aguda, o doente deve ser mantido sob vigilância médica por um períod...

Abordagem e Registo da Anafilaxia em Portugal

A anafilaxia apresenta uma incidência crescente, particularmente em idade pediátrica. Constituindo uma emergência médica, o sucesso terapêutico depende de uma intervenção precoce e adequada. A adrenalina por via intramuscular constitui o fármaco de eleição para o seu tratamento, devendo a dose ser ajustada ao peso e à idade. Resolvida a reação aguda, o doente deve ser mantido sob vigilância médica por um períod...