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Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysi...

Background: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods: We used data from 3663 population-based studies with 222 million participants that...

Klotho in cancer: potential diagnostic and prognostic applications

Klotho proteins, αKlotho, βKlotho, and γKlotho, exert tumor-suppressive activities via the fibroblast growth factor receptors and multiple cell-signaling pathways. There is a growing interest in Klotho proteins as potential diagnostic and prognostic biomarkers for multiple diseases. However, recent advances regarding their roles and potential applications in cancer remain disperse and require an integrated anal...

Active and sedentary behaviors in youth (6-14 years old): Data from the IAN-AF ...

Background: Strategic health interventions must be guided by effective surveillance systems that monitor population trends and patterns, therefore we aimed to provide youth's (6–14 years) national prevalence estimates of physical activity (PA), active outdoor play (AOP), sedentary behaviur (SB), and structured PA (SPA). Methods: Measures of moderate-to-vigorous PA, SB, AOP, and SPA, were obtained for 719 partic...

Socio-demographic factors associated with physical activity and sitting time pa...

Physical activity (PA) and sedentary behaviours (SB) influence health. Since most people engage in different combinations of both behaviours every day, understanding the socio-demographic characteristics of adults with distinct PA and sitting time (ST) patterns is important to contribute to evidence-based planning of public health strategies. Data from a national survey on diet and activity behaviours (IAN-AF, ...

Height and body-mass index trajectories of school-aged children and adolescents...

Background: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods: For this pooled analysis, we used a database of cardiometabolic risk factors colla...

Medication use in older patients and age-blind approach: narrative literature r...

Introduction The importance of rational drug therapy is increasing with the aging of the population. Since one of the main reasons for inappropriate drug prescribing is also the “age-blind” approach, which results in ageist practices, this narrative literature review focuses on the description of the main barriers related to insufficient individualization of drug regimens associated with such age-blind approach...

Results from Portugal’s 2018 Report Card on Physical Activity for Children and ...

Available evidence indicates that there are still a large proportion of Portuguese children and adolescents that are not sufficiently active and that exceed the recommended levels of screen-time. In Portugal, virtually all students, enrolled in formal education, attain regular Physical Education classes, which is of significance.

National Food, Nutrition, and Physical Activity Survey of the Portuguese Genera...

Auditing national physical activity policies: applications, dissemination and l...

Dietary inflammatory index and inflammatory biomarkers in adolescents from LabM...

Background/objectives: The dietary inflammatory index (DII) is a tool to measure the diet’s inflammatory potential and has been used with adults to predict low-grade inflammation. The present study aims to assess whether this dietary score predicts low-grade inflammation in adolescents. Subjects/methods: The sample comprises 329 adolescents (55.9% girls), aged 12–18 years, from LabMed Physical Activity Study. D...