Introdução: A doença de Machado-Joseph (DMJ) ou ataxia espinocerebelosa do tipo 3 (SCA3) é uma doença neurodegenerativa autossómica dominante de manifestação tardia, que exibe uma prevalência elevada no arquipélago dos Açores (Portugal). O sinal cardinal da doença é a ataxia da marcha, mas outras manifestações são frequentes, nomeadamente a disfagia. Por sua vez, a presença da disfagia é associada à perda de pe...
The aquaculture sector faces uncertainty due to environmental changes, economic factors, and availability of food resources. Conventional aquatic feeds heavily depend on fishmeal. This results in sustainability challenges due to overexploitation of wild fish stocks, rising costs, and environmental impacts, which has driven the search for innovative and sustainable alternatives, such as insects. European Union l...
Objectives: To assess the role of food-producing animals as potential transmission vehicles of Salmonella spp. and E. coli to Humans, in order to understand the epidemiology and population structure of these zoonotic agents in Portugal.
Introdução: De todas as infeções associadas aos cuidados de saúde, as infeções urinárias são das mais frequentes, principalmente pelo uso indevido do cateter urinário. Uma das indicações para o uso de cateter urinário é a retenção urinária. Os enfermeiros devem ter competências na avaliação da retenção urinária, para melhor suportar o processo de tomada de decisão neste âmbito. Objetivos: Avaliar a autoconfianç...
Atualmente, o tópico dos compostos bioativos para a segurança alimentar tem sido alvo de grande foco, sobretudo numa época em que a utilização de desinfetantes químicos e de antibióticos é cada vez mais evitada na área agro-alimentar, dentro de um contexto One Health. Deste modo, o estudo de compostos moleculares com capacidade de inibir a presença de bactérias ou fungos patogénicos ou de promover uma população...
There is a strong demand for plant-based milk substitutes, often low in protein content (<1.5% w/v). Protein-rich pulse seeds and the right processing technologies make it possible to make relevant choices. The major objective of this study was to assess the impact of processing on the nutritional characteristics of beverages with a high impact on health, in particular on digestibility and specific bioactivitie...
The Myrtaceae family, one of the most prominent botanical families, is represented in Brazil with different fruit species, rich in bioactive compounds and gastronomically appreciated. This study aimed to carry out an integrative review on the genus Eugenia, highlighting the pitangueira (E. uniflora L.), cagaiteira (E. dysenterica), grumixameira (E. brasiliensis), pereira (E. klotzschiana O. Berg), and uvaieira ...
Matrix metalloproteinases (MMPs) are proteolytic enzymes that play a crucial role in tumor microenvironment remodeling, contributing to inflammatory and angiogenic processes, and ultimately promoting tumor maintenance and progression. Several studies on bioactive polypeptides isolated from legumes have shown anti-migratory, anti-MMPs, and anti-tumor effects, potentially constituting novel strategies for both th...
Food fortification with bioactive compounds may constitute a way to ameliorate inflammatory bowel diseases (IBDs). Lupin seeds contain an oligomer named deflamin that can reduce IBD's symptoms via MMP-9 inhibition. Here, our goal was to develop a lupin protein concentrate (LPC) enriched in deflamin and to test its application as a food additive to be used as a functional food against colitis. The nutritional pr...
There is a strong demand for plant-based milk substitutes, often low in protein content (<1.5% w/v). Protein-rich pulse seeds and the right processing technologies make it possible to make relevant choices. The major objective of this study was to assess the impact of processing on the nutritional characteristics of beverages with a high impact on health, in particular on digestibility and specific bioactivitie...