Submitted by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2017-06-06T12:13:40Z No. of bitstreams: 1 Mauricio Barreto. End Tb...2016.pdf: 493856 bytes, checksum: 5abb74442d6cf1940ecfc3156bca1989 (MD5); Made available in DSpace on 2017-06-06T12:13:40Z (GMT). No. of bitstreams: 1 Mauricio Barreto. End Tb...2016.pdf: 493856 bytes, checksum: 5abb74442d6cf1940ecfc3156bca1989 (MD5); Background: Diseases occur in p...
The efficacy of vaccines is typically estimated prior to implementation, on the basis of randomized controlled trials. This does not preclude, however, subsequent assessment post-licensure, while mass-immunization and nonlinear transmission feedbacks are in place. In this paper we show how cross-sectional prevalence data post-vaccination can be interpreted in terms of pathogen transmission processes and vaccine...
Recent public health threats have propelled major innovations on infectious disease monitoring, culminating in the development of innovative syndromic surveillance methods. Influenzanet is an internet-based system that monitors influenza-like illness (ILI) in cohorts of self-reporting volunteers in European countries since 2003. We investigate and confirm coherence through the first ten years in comparison with...
After remarkable success of vector control campaigns worldwide, concerns about loss of immunity against Plasmodium falciparum due to lack of exposure to the parasite are relevant since an increase of severe cases in less immune individuals is expected. We present a mathematical model to investigate the impact of reducing exposure to the parasite on the immune repertoire against P. falciparum erythrocyte membran...