45 documents found, page 1 of 5
The disruption of elective procedures due to COVID‑19 in Brazil in 2020
Frio, Gustavo Saraiva; Russo, Letícia Xander; Albuquerque, Cleandro Pires de; Mota, Licia Maria Henrique da; Barros‑Areal, Adriana FerreiraElective procedures were temporarily suspended several times over the course of the pandemic of COVID-19. Monthly data from the Unifed Health System (SUS) were used for the period between January 2008 and December 2020 and the interrupted time series method was used to estimate the efect of the pandemic on the number of elective surgeries and elective procedures that were not performed. Considering a 9-month pe...
Mental health and burnout syndrome among postgraduate students in medical and m...
Pinho, Rebeca da Nóbrega Lucena; Costa, Thais Ferreira; Silva, Nayane Miranda; Barros-Areal, Adriana F.; Salles, André de MattosBackground: The COVID-19 pandemic has led to high levels of physical, psychological, and social stress among health care professionals, including postgraduate students in medical and multidisciplinary residencies. This stress is associated with the intense fear of occupational exposure to SARS-CoV-2, the virus known to cause COVID-19. These professionals are at risk of developing physical and mental illnesses n...
Leprosy detection rate in patients under immunosuppression for the treatment of...
Barroso, Daniel Holanda; Brandão, Jurema Guerrieri; Andrade, Elaine Silva Nascimento; Correia, Ana Clara Banhatto; Aquino, Danielle CostaBackground: Recently developed immunosuppressive drugs, especially TNF antagonists, may enhance the risk of granulomatous infections, including leprosy. We aimed to evaluate the leprosy detection rate in patients under immunosuppression due to rheumatological, dermatological and gastroenterological diseases. Methods: We performed a systematic review of the literature by searching the PubMed, EMBASE, LILACS, Web...
A comprehensive systematic review of leishmaniasis in patients undergoing drug-...
Kurizky, Patricia Shu; Marianelli, Fernanda Ferraço; Cesetti, Mariana Vicente; Damiani, Giovanni; Sampaio, Raimunda Nonata RibeiroImmunosuppression is an important risk factor for leishmaniasis. We assessed the clinical profile, geographic distribution and prevalence of leishmaniasis in patients undergoing immunosuppressive therapy for dermatological, rheumatological or gastroenterological autoimmune diseases. We identified relevant studies in PubMed, EMBASE, Scopus, Web of Science and LILACS on July 3rd, 2018. We included articles that r...
Enhanced il-6 and il-12b gene expression after SARS-CoV-2 infection in leprosy ...
Morais Júnior, Gilberto Santos; Kurizky, Patricia Shu; Cerqueira, Selma Regina Penha Silva; Barroso, Daniel Holanda; Schulte, Heidi LuiseExperts have called attention to the possible negative impact of the coronavirus disease 2019 (COVID19)–related cytokine storm syndrome on the progression of leprosy-related disabilities. We assessed the frequency of reactional states in patients co-infected with Mycobacterium leprae and severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 (SARS-CoV-2). We consecutively included patients during the firs...
Impact of chronic use of antimalarials on SARS-CoV-2 infection in patients with...
Gomides, Ana; Ferreira, Gilda; Kakehasi, Adriana; Lacerda, Marcus; Marques, Cláudia; Mota, Licia Maria Henrique da; Paiva, Eduardo; Pileggi, GecilmaraBackground: COVID-19, caused by the virus SARS-CoV-2, has brought extensive challenges to the scientific community in recent months. Several studies have been undertaken in an attempt to minimize the impact of the disease worldwide. Although new knowledge has been quickly disseminated, including viral mechanisms, pathophysiology, and clinical findings, there is a lack of information on the effective pharmacolog...
Enhanced il-6 and il-12b gene expression after SARS-CoV-2 infection in leprosy ...
Morais Júnior, Gilberto Santos; Kurizky, Patricia Shu; Cerqueira, Selma Regina Penha Silva; Barroso, Daniel Holanda; Schulte, Heidi LuiseExperts have called attention to the possible negative impact of the coronavirus disease 2019 (COVID-19)–related cytokine storm syndrome on the progression of leprosy-related disabilities. We assessed the frequency of reactional states in patients co-infected with Mycobacterium leprae and severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 (SARS-CoV-2). We consecutively included patients during the fir...
Validation of a yellow fever vaccine model using data from primary vaccination ...
Bonin, Carla Rezende Barbosa; Fernandes, Guilherme Côrtes; Martins, Reinaldo de Menezes; Camacho, Luiz Antonio Bastos; Carvalho, Andréa TeixeiraBackground: An effective yellow fever (YF) vaccine has been available since 1937. Nevertheless, questions regarding its use remain poorly understood, such as the ideal dose to confer immunity against the disease, the need for a booster dose, the optimal immunisation schedule for immunocompetent, immunosuppressed, and pediatric populations, among other issues. This work aims to demonstrate that computational too...
SARS-CoV-2/DENV co-infection : a series of cases from the Federal District, Mid...
Schulte, Heidi Luise; Sousa, José Diego Brito; Lacerda, Marcus Vinícius Guimarães de; Naves, Luciana Ansaneli; Gois, Eliana Teles deBackground: Since the novel coronavirus disease outbreak, over 179.7 million people have been infected by SARS-CoV-2 worldwide, including the population living in dengue-endemic regions, particularly Latin America and Southeast Asia, raising concern about the impact of possible co-infections. Methods: Thirteen SARS-CoV-2/DENV co-infection cases reported in Midwestern Brazil between April and September of 2020 a...
Brazilian recommendations on the safety and effectiveness of the yellow fever v...
Pileggi, Gecilmara Salviato; Mota, Licia Maria Henrique da; Kakehasi, Adriana Maria; Souza, Alexandre Wagner de; Rocha, Aline; Melo, Ana Karla Guedes deBackground: In Brazil, we are facing an alarming epidemic scenario of Yellow fever (YF), which is reaching the most populous areas of the country in unvaccinated people. Vaccination is the only effective tool to prevent YF. In special situations, such as patients with chronic immune-mediated inflammatory diseases (CIMID), undergoing immunosuppressive therapy, as a higher risk of severe adverse events may occur,...