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Describing variability in pig (Sus scrofa) genes coding for receptors and primi...

Bovo, S.; Schiavo, G.; Ribani, A.; Utzeri, V.J.; Taurisano, V.; Ballana, M.; Muñoz, M.; Alves, E.; Araújo, J.P.; Bozzi, R.; Charneca, R.; Di Palma, F.

Coronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral infections. However, at present there is no example that considers pig genetic resources in this context. In this study, we investigated the variability of four genes (ACE2, ANPEP and DPP4 encoding for host rec...


Genome-wide detection of copy number variants in European autochthonous and com...

Bovo, S.; Ribani, A.; Muñoz, M.; Alves, E.; Araujo, J.P.; Bozzi, R.; Charneca, R.; Palma, F.D.; Etherington, G.; Fernandez, A.I.; García, F.

In this study, we identified copy number variants (CNVs) in 19 European autochthonous pig breeds and in two commercial breeds (Italian Large White and Italian Duroc) that represent important genetic resources for this species. The genome of 725 pigs was sequenced using a breed-specific DNA pooling approach (30–35 animals per pool) obtaining an average depth per pool of 429. This approach maximised CNV discovery...


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