11 documents found, page 1 of 2

Imperativo da Avaliação Integrada para um Envelhecimento Ativo e Saudável

Ageing in Place: Older People Identify Barriers to Remaining in Low-Density Areas

Studies involving older people as co-investigators are limited in Portugal. The main objectives of this article are: (I) Analyze the barriers identified by older people living in low-density territories that pose a challenge to ageing in place. (ii) Understand the co-research methodology as an appropriate instrument for increasing the participatory capacity of older people and improving the conditions for agein...

Epigenetic alterations in urothelial bladder cancer associated with disease out...

Objectives Bladder cancer (BLCA) is a molecular heterogeneous disease with known genetic distinctive signatures. However, DNA methylation is highly prevalent across a wide range of tumors, suggesting its potential in oncogenesis. Here, we aimed to interrogate the role of nine epigenetic alterations as diagnostic and prognostic markers in BLCA. Methods DNA methylation, gene expression, and clinicopathological in...

Prevalence and Management of Incidental Testicular Masses—A Systematic Review

Abstract: Management of incidentally diagnosed small testicular masses (STM) is controversial. Although there is the risk of malignancy, it might be realistic to safely seek preservation of testicles bearing benign masses. This study aims to systematically evaluate the evidence regarding prevalence of STMs, their benign or malignant histology and their management. We conducted a systematic literature search for...

Advanced Maternal Age: Adverse Outcomes of Pregnancy, A Meta-Analysis

The risks of pregnancy in women of advanced maternal age are not consensual amongst studies. The aim of this metaanalysis  was to determine whether women of advanced maternal age (≥ 35 years old) had worse obstetrical and perinatal outcomes than non- advanced maternal age women (20 - 34 years old) in singleton, naturally-conceived pregnancies.Material and Methods: We searched PubMed/ MEDLINE, IndexRMP and the C...

Assessing Functional Capacity and Factors Determining Functional Decline in the...

Introduction: The aim of this study is to assess functional capacity and determine the factors associated with functional decline in the elderly in adult day care centres and home care support in the County of Coimbra, Portugal. Material and Methods: Cross-sectional study. A total of 115 participants of both genders, aged between 65 and 98, were enrolled in the home care support and adult day care system of the...

Advanced Maternal Age: Adverse Outcomes of Pregnancy, A Meta-Analysis

Introduction: The risks of pregnancy in women of advanced maternal age are not consensual amongst studies. The aim of this metaanalysis  was to determine whether women of advanced maternal age (≥ 35 years old) had worse obstetrical and perinatal outcomes than non- advanced maternal age women (20 - 34 years old) in singleton, naturally-conceived pregnancies.Material and Methods: We searched PubMed/ MEDLINE, Inde...

Fatores Relevantes na Avaliação Cognitiva da População Portuguesa

Introdução: O envelhecimento é um processo inevitável que tem um impacto social e será nas próximas décadas o grande desafio em termos de saúde pública. Um sistema de saúde eficiente requer uma reflexão sobre as medidas preventivas a aplicar. Material e Métodos: A amostra em estudo englobou 2672 indivíduos de ambos os géneros, com idade igual ou superior a 55 anos, residentes em Portugal continental, ao qual fo...

Obesity and infection - the challenge of tropical medicine

The World Health Organization currently considers obesity a worldwide epidemic. A perspective of the past considered overeating and a sedentary lifestyle as main factors of this major public health problem. However, other risk factors can be associated, such as heredity, sleep disorders and the action of microbial agents. Regarding the association of obesity with infection, it appears that some microorganisms s...

NSAID HYPERSENSITIVITY AND BASOPHIL ACTIVATION TEST

Introduction: Allergy to nonsteroidal anti-inflammatory drugs (NSAIDs) is often associated with severe hypersensitivity reactions and with difficult diagnosis. Basophil activation test by flow cytometry with Flow2cast (BAT) is a novel in vitro test for identification of hypersensitivity reactions to these drugs but with some limitations.Clinical case: Young male manifesting chronic urticaria since childhood pre...