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Transcriptomic and metabolomic profiling of ionic liquid stimuli unveils enhanc...

Alves, Paula C.; Hartmann, Diego O.; Núñez, Oscar; Martins, Isabel; Gomes, Teresa L.; Garcia, Helga; Galceran, Maria Teresa; Hampson, Richard

The inherent potential of filamentous fungi, especially of Ascomycota, for producing diverse bioactive metabolites remains largely silent under standard laboratory culture conditions. Innumerable strategies have been described to trigger their production, one of the simplest being manipulation of the growth media composition. Supplementing media with ionic liquids surprisingly enhanced the diversity of extracel...


Elucidating how the saprophytic fungus Aspergillus nidulans uses the plant poly...

Martins, Isabel; Hartmann, Diego O; Alves, Paula C; Martins, Celso; Garcia, Helga; Leclercq, Céline C; Ferreira, Rui; He, Ji; Renaut, Jenny

Lipid polymers in plant cell walls, such as cutin and suberin, build recalcitrant hydrophobic protective barriers. Their degradation is of foremost importance for both plant pathogenic and saprophytic fungi. Regardless of numerous reports on fungal degradation of emulsified fatty acids or cutin, and on fungi-plant interactions, the pathways involved in the degradation and utilisation of suberin remain largely o...


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