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The SOUL family of heme-binding proteins: structure and function 15 years later

Goodfellow, Brian J.; Freire, Filipe; Carvalho, Ana Luísa; Aveiro, Susana S.; Charbonnier, Peggy; Moulis, Jean-Marc; Delgado, Leonildo

The SOUL, or heme-binding protein HBP/SOUL, family represents a group of evolutionary conserved putative heme-binding proteins that contains a number of members in animal, plant and bacterial species. The structures of the murine form of HEBP1, or p22HBP, and the human form of HEBP2, or SOUL, have been determined in 2006 and 2011 respectively. In this work we discuss the structures of HEBP1 and HEBP2 in light o...


The SOUL family of heme-binding proteins: structure and function 15 years later

Goodfellow, Brian J.; Freire, Filipe; Carvalho, Ana Luísa; Aveiro, Susana; Charbonnier, Peggy; Moulis, Jean-Marc; Delgado, Leonildo; Ferreira, Gloria C.

The SOUL, or heme-binding protein HBP/SOUL, family represents a group of evolutionary conserved putative heme-binding proteins that contains a number of members in animal, plant and bacterial species. The structures of the murine form of HEBP1, or p22HBP, and the human form of HEBP2, or SOUL, have been determined in 2006 and 2011 respectively. In this work we discuss the structures of HEBP1 and HEBP2 in light o...


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