20 documents found, page 1 of 2
Reputation risk mitigation in investment strategies
Moura, Alexandra; Oliveira, CarlosWe consider an investment model in which a firm decides to invest in the market, taking into account its future revenue and the possible occurrence of adverse events that may impact its reputation. The firm can buy an insurance contract at the investment time to mitigate reputation risk. The firm decides when to enter the market and the insurance strategy that maximizes its value. We consider three types of ins...
Building a hurricane risk map for continental Portugal based on loss data from ...
Hauser, Andrea; Rosa, Carlos; Esteves, Rui Esteves; Moura, Alexandra; Oliveira, CarlosA complete model to analyse and predict future losses in the property portfolio of an insurance company due to hurricanes is proposed. A novel statistical model, in which weather data is not required, is considered. Climate data may not be reliable, or may be difficult to deal with or to obtain, hence we reconstruct the storm behaviour through the registered claims and respective losses. The model is calibrated...
Retrospective validation of whole genome sequencing-enhanced surveillance of li...
Van Walle, Ivo; Björkman, Jonas Torgny; Cormican, Martin; Dallman, Timothy; Mossong, Joël; Moura, Alexandra; Pietzka, Ariane; Ruppitsch, WernerBackground and aim: The trend in reported case counts of invasive Listeria monocytogenes (Lm), a potentially severe food-borne disease, has been increasing since 2008. In 2015, 2,224 cases were reported in the European Union/European Economic Area (EU/ EEA). We aimed to validate the microbiological and epidemiological aspects of an envisaged EU/EEAwide surveillance system enhanced by routine whole genome sequen...
Risk factors for mortality in end-stage kidney disease patients under online-he...
Sousa-Martins, Pedro; Moura, Alexandra; Madureira, José; Alija, Pablo; Oliveira, José Gerardo; Lopez, Martin; Filgueiras, Madalena; Amado, LeonildeEnd-stage kidney disease (ESRD) patients under dialysis have high mortality rate. Infl ammation, poor nutritional status and disturbances in erythropoiesis and iron metabolism have been reported in these patients. Moreover, there is a growing concern about the health related quality of life (HRQOL) in the context of ESRD. The aim of this work was to study the predictive value of these disturbances, dialysis ade...
Effect of aging in the perception of health-related quality of life in end-stag...
Moura, Alexandra; Madureira, José; Alija, Pablo; Fernandes, João Carlos; Oliveira, José Gerardo; Lopez, Martin; Filgueiras, Madalena; Amado, LeonildeThis work aimed to evaluate how aging could influence patients' perception of health quality of life (HRQOL), as well as, the effect of aging on dialysis adequacy and in hematological, iron status, inflammatory and nutritional markers. In this transversal study were enrolled 305 ESRD patients under online-hemodiafiltration (OL-HDF) (59.67% males; 64.9 ± 14.3 years old). Data about comorbidities, hematological d...
The contribution of Escherichia coli from human and animal sources to the integ...
Moura, Alexandra; Araújo, Susana; Alves, Marta S.; Henriques, Isabel; Pereira, Anabela; Correia, António C. M.To understand the contribution of animal- and human-derived fecal pollution sources in shaping integron prevalence and diversity in beach waters, 414 Escherichia coli strains were collected from beach waters (BW, n = 166), seagull feces (SF, n = 179), and wastewaters (WW, n = 69), on the World Biosphere Reserve of the Berlenga Island, Portugal. Statistical differences were found between the prevalence of integr...
Co-resistance to different classes of antibiotics among ESBL-producers from aqu...
Tacão, Marta; Moura, Alexandra; Correia, António; Henriques, IsabelIn this study we investigated the co-occurrence of resistance to non-beta-lactams among cefotaxime-resistant extended-spectrum beta-lactamase (ESBL) producers (ESBL+) versus non-ESBL producers (ESBL-), from aquatic environments. Higher prevalence of resistance to tetracycline, fluoroquinolones and aminoglycosides were observed in ESBL+. Among ESBL+ resistant to tetracycline (n=18), tet(A) was detected in 88.9% ...
Relative amino acid composition signatures of organisms and environments
Moura, Alexandra; Savageau, Michael A.; Alves, RuiBACKGROUND: Identifying organism-environment interactions at the molecular level is crucial to understanding how organisms adapt to and change the chemical and molecular landscape of their habitats. In this work we investigated whether relative amino acid compositions could be used as a molecular signature of an environment and whether such a signature could also be observed at the level of the cellular amino a...
Comparative genomics of IncP-1ε plasmids from water environments reveals divers...
Oliveira, Cláudia S.; Moura, Alexandra; Henriques, Isabel; Brown, Celeste J.; Rogers, Linda M.; Top, Eva M.; Correia, AntónioThe goal of this study was to determine and compare the complete genome sequences of three new broad-host-range conjugative plasmids. Plasmids pMLUA1, pMLUA3 and pMLUA4 were previously recovered from estuarine water by exogenous plasmid isolation and ranged in size from ~55 to 59. kb. Comparative genomics showed that their backbone region was identical to the prototype pKJK5 and other IncP1-ε plasmids captured ...
Broad diversity of conjugative plasmids in integron-carrying bacteria from wast...
Moura, Alexandra; Oliveira, Cláudia; Henriques, Isabel; Smalla, Kornelia; Correia, AntónioIn this study we assessed the occurrence, diversity and conjugative potential of plasmids in integron-carrying Aeromonas and Enterobacteriaceae from wastewaters. Sixty-six strains were included as donors in mating assays using rifampicin-resistant Escherichia coli and Pseudomonas putida recipient strains. The diversity of plasmids from donors and transconjugants (resistant to tetracycline or streptomycin) was e...