49 documents found, page 1 of 5
Preserving and hydrogel-matrixing the bioactive properties of aromatic medicina...
Parracho, Tiago; Cruz, Pedro F.; Peralta, Claúdia C.; Silva, Cândida G.; Campos, Maria Jorge; Neves, Marta; Cordeiro, Rachel; Trindade, DanielaEdible wild plants are part of the ethnobotanic heritage of a certain geographical area and are important sources of essential oils, antioxidants, minerals, and special flavours. Corema album (Portuguese crowberry), Crithmum maritimum (sea fennel), Eryngium maritimum (sea holly), Helichrysum italicum (curry plant) and Otanthus maritimus (cottonweed) wildly flourish along the sandy dunes of the coast of the Iber...
A data-driven intelligent decision support system that combines predictive and ...
Ribeiro, Rui; Pilastri, Andre; Moura, Carla; Morgado, Jose; Cortez, PauloIn this paper, we propose an Intelligent Decision Support System (IDSS) for the design of new textile fabrics. The IDSS uses predictive analytics to estimate fabric properties (e.g., elasticity) and composition values (% cotton) and then prescriptive techniques to optimize the fabric design inputs that feed the predictive models (e.g., types of yarns used). Using thousands of data records from a Portuguese text...
Eco-friendly flagging tape
Cordeiro, Rachel; Meneses, João; Dourado, Fernando; Pascoal-Faria, Paula; Moura, Carla; Alves, NunoOne of the problems of using commercial flagging tapes is that they are produced with non-degradable plastic and remain in the environment for long periods. To find a solution, an eco-friendly flagging tape was developed. Bacterial cellulose (BC) was used to produce a cellulose-based film and it was hypothesised that coating the tapes with a polymer would improve their resistance. So, two natural polymers (chit...
Development of a biocompatible hydrogel based on native temporomandibular joint...
Trindade, Daniela; Moura, Carla; Calado, Cecília; Ângelo, David; Alves, NunoThe temporomandibular joint disc (TMJd) is an avascular and fibrocartilaginous tissue with low regeneration capacities. To date there is no permanent solution upon its damage. So, our group hypothesise that the combination of a synthetic material [poly(ethylene glycol) diacrylate, PEGDA] and decellularised matrices may be the answer, since it has the advantage of retaining extracellular matrix (ECM) components....
Multifunctional bacterial cellulose-chitosan tape: an innovative substitute for...
Cordeiro, Rachel; Meneses, João; Dourado, Fernando; Veloso, Ana C. A.; Pascoal-Faria, Paula; Alves, Nuno; Moura, CarlaSynthetic polymers, generically named plastics, are manufactured from non-renewable sources, such as fossil fuels [1]. In 2020, 367 million metric tons of plastic were produced worldwide, and, only in 2018, global plastic waste volume reached 342.6 million metric tons [2,3]. One of the most used plastics is polyvinyl chloride (PVC), which is not environmentally friendly. The goal of this study was to achieve an...
Development of a biocompatible hydrogel based on native temporomandibular joint...
Trindade, Daniela; Moura, Carla; Calado, Cecília; Ângelo, David; Alves, NunoThe temporomandibular joint disc (TMJd) is an avascular and fibrocartilaginous tissue with low regeneration capacities. To date there is no permanent solution upon its damage. So, our group hypothesise that the combination of a synthetic material [poly(ethylene glycol) diacrylate, PEGDA] and decellularised matrices may be the answer, since it has the advantage of retaining extracellular matrix (ECM) components....
Ovine model as a temporomandibular disc substitute: characterisation and the ou...
Trindade, Daniela; Calado, Cecília; Alves, Nuno; Moura, CarlaThe temporomandibular joint (TMJ) is a ginglymoarthrodial joint that comprises a fibrocartilaginous disc that is highly predisposed to suffer from trauma or degenerative events, leading to disorders in the condyle–disc complex. The use of decellularized tissues has attracted interest in the tissue engineering (TE) field as an intact extracellular matrix can be obtained [1]. To this end, the ovine model was the ...
Corncob cellulose scaffolds: A new sustainable temporary implant for cartilage ...
Cordeiro, Rachel; Henriques, Marta; Silva, João C.; Antunes, Filipe; Alves, Nuno; Moura, CarlaTissue engineering using scaffolds is a promising strategy to repair damaged articular cartilage, whose self-repair is inefficient. Cellulose properties have been recognized for their application in the biomedical field. The aim of this study was to fabricate and characterize novel scaffolds based on poly(E-caprolactone) (PCL) and sustainable cellulose. Thus, the performance of corncob-derived cellulose (CC) in...
From animal to human: (Re)using acellular extracellular matrices for temporoman...
Trindade, Daniela; Alves, Nuno; Moura, CarlaCurrent treatments for temporomandibular joint (TMJ) disc dysfunctions are not fully effective and lack regenerative capacity. Therefore, the search for tissue-engineered materials for TMJ disc substitution is critical to fill this gap. Decellularization presents tremendous potential, as it is possible to obtain an extracellular matrix with an adequate biomechanical structure and biochemical components. However...
Additive manufactured Poly("-caprolactone)-graphene scaffolds: Lamellar crystal...
Biscaia, Sara; Silva, João C.; Moura, Carla; Viana, Tânia; Tojeira, Ana; Mitchell, Geoffrey R.; Pascoal-Faria, Paula; Ferreira, Frederico CasteloUnderstanding the mechano–biological coupling mechanisms of biomaterials for tissue engineering is of major importance to assure proper scaffold performance in situ. Therefore, it is of paramount importance to establish correlations between biomaterials, their processing conditions, and their mechanical behaviour, as well as their biological performance. With this work, it was possible to infer a correlation be...