4 documents found, page 1 of 1
One-Pot Microfluidics to Engineer Chitosan Nanoparticles Conjugated with Antimi...
Fonseca, D R; Alves, PM; Neto, E; Custodio, B; Guimaraes, S; Moura, D; Annis, F; Martins, M; Gomes, A; Teixeira, C; Gomes, P; Pereira, RF; Freitas, PSurface bioconjugation of antimicrobial peptides (AMP) onto nanoparticles (AMP-NP) is a complex, multistep, and time-consuming task. Herein, a microfluidic system for the one-pot production of AMP-NP was developed. Norbornene-modified chitosan was used for NP production (NorChit-NP), and thiolated-AMP was grafted on their surface via thiol-norbornene "photoclick" chemistry over exposure of two parallel UV LEDs....
Cessação tabágica no doente internado
Moura, D; Guerreiro, S; Soares, S
Imidazoline receptors. Historic review and current status of knowledge.
Moura, DAfter the initial demonstration, by Ruffolo in 1977, that imidazolines and phenethylamines do not interact in the same manner with adrenoceptors, a different class of receptors (imidazoline-preferring receptors) was identified. They are present in the brain stem and in several tissues at the periphery. This imidazoline-preferring receptor is believed to be the target of the anti-hypertensive effect of clonidine...
Drug activation of GABAergic transmission in the central nervous system: benzod...
Moura, D; Soares-da-Silva, P