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Eligibility criteria for biologic disease-modifying antirheumatic drugs in axia...

Marona, José; Sepriano, Alexandre; Rodrigues Manica, Santiago; M. Pimentel-Santos, F.; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime; Santos, Helena

This work was supported by a Research Grant from the InvestigatorInitiated Studies program of Merck Sharp & Dohme (Grant No. 56078). The sponsor did not interfere with the study question, analysis or interpretation of results. AS is supported by a doctoral grant from Fundação para a Ciência e Tecnologia (Foundation for Science and Technology) (SFRH/BD/108246/2015).; OBJECTIVES: To compare definitions of high di...


Effectiveness of switching between TNF inhibitors in patients with axial spondy...

Rodrigues Manica, Santiago; Sepriano, Alexandre; M. Pimentel-Santos, F.; Gouveia, Nélia; Barcelos, Anabela; Branco, Jaime; Bernardes, Miguel

57763]. AS is supported by a doctoral grant from “Fundação para a Ciência e Tecnologia” (SFRH/BD/108246/2015).; Background: To investigate whether the reason to discontinue the first TNF inhibitor (TNFi) affects the response to the second TNFi in axial spondyloarthritis (axSpA). Methods: Patients with axSpA from the Rheumatic Diseases Portuguese Register (ReumaPt), who discontinued their first TNFi and started ...


Guia prático de utilização de terapêuticas biotecnológicas na artrite reumatóid...

Mourão, Ana Filipa; Fonseca, João Eurico; Canhão, Helena; Santos, Maria José; Bernardo, Alexandra; Cordeiro, Ana; Cravo, Ana Rita; Ribeiro, Ana

The authors review the practical aspects of biologi -cal therapy use for rheumatoid arthritis patients, commenting safety issues before and after treatment initiation and the best treatment strategies to optimize efficacy.


Guia prático de utilização de terapêuticas de biotecnologia na artrite reumatóide

Fonseca, Joao Eurico; Canas Silva, J. A.; Canhão, Helena; Santos, Maria Jose; Barcelos, Anabela; Ines, Luis; Costa, Maria Lucia; Rodrigues, Mario


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