2 documents found, page 1 of 1
Circulating micrornas correlate with multiple myeloma and skeletal osteolytic l...
Moura, SR; Abreu, H; Cunha, C; Ribeiro-Machado, C; Oliveira, CM; Barbosa, MA; Marques, H; Almeida, MIMultiple myeloma (MM) is the second most frequent hematological disease and can cause skeletal osteolytic lesions. This study aims to evaluate the expression of circulating microRNAs (miR-NAs) in MM patients and to correlate those levels with clinicopathological features, including bone lesions. A panel of miRNAs associated with MM onset and progression, or with bone remodeling, was analyzed in the plasma of 82...
Long noncoding RNAs: a missing link in osteoporosis
Silva, AM; Moura, SR; Teixeira, JH; Barbosa, MA; Santos, SG; Almeida, MIOsteoporosis is a systemic disease that results in loss of bone density and increased fracture risk, particularly in the vertebrae and the hip. This condition and associated morbidity and mortality increase with population ageing. Long noncoding (lnc) RNAs are transcripts longer than 200 nucleotides that are not translated into proteins, but play important regulatory roles in transcriptional and post-transcript...