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Seasonal, spatial, and high-frequency monitoring of dissolved oxygen and net ec...
Correia, Cátia; Jacob, José; Cravo, AlexandraThis study provides a detailed assessment of dissolved oxygen (DO) dynamics and net ecosystem metabolism (NEM) in the Ria Formosa coastal lagoon, highlighting how spatial and temporal variability shape mesotidal ecosystems. Complementary approaches were applied: short-term (24 h) diel oxygen open-water method at two stations (eastern and western boundaries) in comparison with the bottle incubation method, and a...
Seasonal, spatial, and high-frequency monitoring of dissolved oxygen and net ec...
Correia, Cátia; Jacob, José; Cravo, AlexandraThis study provides a detailed assessment of dissolved oxygen (DO) dynamics and net ecosystem metabolism (NEM) in the Ria Formosa coastal lagoon, highlighting how spatial and temporal variability shape mesotidal ecosystems. Complementary approaches were applied: short-term (24 h) diel oxygen open-water method at two stations (eastern and western boundaries) in comparison with the bottle incubation method, and a...
Water quality for bivalve molluscs and consumer safety: application of novel an...
Cravo, Alexandra; Barbosa, Ana; Borlido Oliveira Lima, Maria João; Ferreira, Cristina; Correia, Cátia; Matos, André Filipe; Jacob, José; Caetano, SandraWater quality degradation associated with wastewater discharges compromises the production of marine living resources. Water quality indices (WQIs) are relevant tools for water quality management, but most applications are limited to the suitability of freshwater for drinking. In this study, a novel WQI was developed to assess the effects of urban wastewater treatment plant (WWTP) discharges on the water qualit...
A critical analysis of the marina environmental risk assessment method applied ...
Neves, Maria C.; Cravo, Alexandra; Jacob, José; Correia, CátiaThe MERA (Marina Environmental Risk Assessment) procedure was applied for the first time along the coast of Portugal to classify the risk of 26 marinas on water quality. A risk ranking Atlas was produced to provide managers or decision-makers with spatial information that can help achieve sustainable development goals. The results indicate that the eight marinas in the south coast of the country (Algarve) face ...
Dynamics of CO2, CH4, and N2O in Ria Formosa coastal lagoon (southwestern Iberi...
Sierra, A.; Ortega, T.; Forja, J.; Rodrigues, M.; Cravo, Alexandra; Correia, CátiaA first characterization of greenhouse gases had been carried out to study their role and impact in a productive transitional coastal system of the southern Portugal – Ria Formosa lagoon. To this purpose, the partial pressure of CO2 (pCO2) and the concentration of dissolved CH4 and N2O have been measured. Two surveys were carried out during 2020, at low tide under typical conditions of Spring (March) and end of...
Integrating physical and biogeochemical processes and oceanic exchanges at a co...
Cravo, Alexandra; Jacob, José; Rosa, Alexandra; Correia, CátiaCoastal lagoons are highly productive systems and the quantification of mass fluxes, which is of paramount importance for the sustainable management of these systems, remains poorly studied. In this context, a detailed study was conducted to better understand the exchanges between the productive coastal lagoon Ria Formosa (South-West Europe) and the ocean. The exchanges of water, nutrients, chlorophyll-a and su...
A conformational-dependent interdomain redox relay at the core of protein disul...
Pinho Melo, Eduardo; El-Guendouz, Soukaina; Correia, Cátia; Morais, Fernando Jorge Teodoro Duarte Garcia; Lopes, CarlosProtein disulfide isomerases (PDIs) are a family of molecular chaperones resident in the endoplasmic reticulum (ER) emerging as important factors in disease. In addition to an holdase function, some members catalyse disulfide bond formation and isomerization, a crucial step for native folding and prevention of aggregation of misfolded proteins. PDIs are characterized by a modular arrangement of thioredoxin-like...
Bioadhesive hyaluronic acid-based hydrogels for spinal cord injury
Duarte, Diogo; Correia, Cátia; Reis, R. L.; Pashkuleva, I.; Peixoto, Daniela; Alves, N. M.Spinal cord injuries (SCI) have devastating physical, psychological, and psycho-social consequences for patients. One challenge of nerve tissue repair is the lack of a natural extracellular matrix (ECM) that guides the regenerating axons. Hyaluronic acid (HA) is a major ECM component and plays a fundamental role in facilitating lesion healing. Herein, we developed HA-based adhesive hydrogels by modification of ...
Fate of microbial contamination in a South European Coastal Lagoon (Ria Formosa...
Caetano, Sandra; Correia, Cátia; Torres, Ana Flor; Matos, André Filipe; Ferreira, Cristina; Cravo, AlexandraAim: Assessment of the fate of microbial contamination driven from treated wastewater disposal at a highly productive zone on a South European coastal lagoon (Ria Formosa). Methods and results: Microbial indicators of contamination (Total coliforms, Escherichia coli and Enterococci) were evaluated monthly during September 2018-September 2020, at three study areas (Faro, Olhão, Tavira) under different wastewater...
Human stem cells for cardiac disease modeling and preclinical and clinical appl...
Correia, Cátia; Ferreira, Anita; Fernandes, Mónica T.; Silva, Bárbara M.; Esteves, Filipa; Leitao, Helena; Bragança, José; Calado, SofiaCardiovascular diseases (CVDs) are pointed out by the World Health Organization (WHO) as the leading cause of death, contributing to a significant and growing global health and economic burden. Despite advancements in clinical approaches, there is a critical need for innovative cardiovascular treatments to improve patient outcomes. Therapies based on adult stem cells (ASCs) and embryonic stem cells (ESCs) have ...