2 documents found, page 1 of 1
Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hal...
Nunes, Maria João; Carvalho, Andreia Neves; Reis, Joana; Costa, Daniela; Moutinho, Miguel; Mateus, Joana; Mendes de Almeida, Rita; Brito, SaraFunding Information: This work was funded by FEDER and by National Funds through Fundação para a Ciência e a Tecnologia (FCT) under project PTDC/MED-NEU/29455/2017 , Bolsa de Investigação da Sociedade Portuguesa de Doenças Metabólicas (SPDM), and BrainVectis Technologies . Publisher Copyright: © 2023 The Authors; Cholesterol 24-hydroxylase (CYP46A1) is an exclusively neuronal cytochrome P450 enzyme responsible ...
Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic mark...
Moutinho, Miguel; Nunes, Maria João; Correia, Jorge C.; Gama, Maria João; Castro-Caldas, Margarida; Cedazo-Minguez, Angel; Rodrigues, Cecília M PWe are deeply thankful to Professor David W. Russell (University of Texas Southwestern Medical Center) for the kind gift of the anti-CYP46A1 antibody. This work was supported by FEDER (COMPETE Programme) and national funds from Fundacao para a Ciencia e a Tecnologia (FCT), Portugal, research grants iMed.ULisboa (UID/DTP/04138/2013), PTDC/SAU/NMC/110809/2009 (to E.R.), SFRH/BD/78041/2011 (to M.M.) SFRH/BPD/95855...