Previous studies using immunoassays for steroid measurements have focused on the association between steroid hormone levels and bone mineral density (BMD) in postmenopausal women, obtaining contradictory results. This study aimed to assess this association using a highly sensitive bioanalytical method. A total of 68 postmenopausal women, aged 65–89 years, were enrolled in a crosssectional study. Measurements of...
O cancro do colo do útero (CCU) é globalmente um dos tipos de cancro mais comum em mulheres. O rastreio do CCU é indispensável para a deteção e tratamento de lesões neoplásicas cervicais que possam evoluir para neoplasia, com o objectivo de reduzir a incidência deste cancro. Nos últimos anos, têm ocorrido alterações que visam o aumento da eficácia do rastreio. Nomeadamente, o uso de teste de deteção do vírus do...
This study aims to clarify the effect of postmenopausal bilateral oophorectomy on plasma steroid hormone levels. Women who were submitted in the postmenopausal period to hysterectomy for uterine benign conditions were divided into two groups: 18 women had isolated hysterectomy and 11 had hysterectomy with bilateral salpingo-oophorectomy. In both groups serum hormone levels were quantified by solid phase extract...
Cardiotoxicity is a known complication and one of the most adverse effects from the use of conventional treatments such as anthracyclines and trastuzumab in breast cancer (BC) care. This phenomenon has been associated with the restriction of therapeutic options and the increase of cardiovascular complications, which may compromise the survival of patients. Implementation of preventive strategies is an important...
After breast cancer diagnosis (BCD), localized breast cancer (BC) patients are treated with curative intent by several therapeutic modalities. Despite the benefit of those therapies, the induction of side effects is acommon consequence affecting psychosocial and physiological outcomes. This quasi-experimental study compared physical fitness in recent-term (14–30 months; n= 11) and later-term (74–92 months; n= 8...
Por ano em todo o mundo, são diagnosticados cerca de 1.3 milhões de novos casos de cancro mama. Recentemente, o tratamento do cancro da mama obteve progressos substanciais, com consequente aumento de sobreviventes. No entanto, apesar dos benefícios destes tratamentos, o desenvolvimento de efeitos secundários é uma realidade, destacando-se a fadiga, a diminuição da aptidão física e da qualidade devida. Assim, po...
The detection of fertile and ovulation periods may be performed by women’s body temperature variations. These variations are more accurate if a core-body temperature for their detection is used. Previous medical studies concluded that the use of skin temperature could be influenced by environmental conditions. Since the increasing of the body temperature in this period is only about 0.5 ºC, it is crucial that m...
Body Area Sensor can enable healthcare monitoring in an unobtrusive way. Medical and healthcare research has been striving to find relationships between core body temperature at female genitals and certain health conditions, such as ovulation period. This paper presents a solution for intra-body temperature monitoring based on a new intra-body sensor, communication and desktop application tool. This new biosens...
A aplicação de novas contribuições científicas para a análise de processos fisiológicos deu origem a uma nova era na medicina, introduzindo técnicas e dispositivos para medição e monitorização de parâmetros fisiológicos. Este trabalho tem como objectivo a apresentação de um novo sensor de temperatura para medição e monitorização da temperatura intra-vaginal. Esta monitorização irá permitir estudar as variações ...